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PRKG1 Protein (His tag)

PRKG1 宿主: 人 宿主: 人细胞 Recombinant > 80 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318303
发货至: 中国
  • 抗原 See all PRKG1 蛋白
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 3
    • 1
    资源
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This PRKG1 protein is labelled with His tag.
    原理
    Recombinant Human PRKG1 Protein (His Tag)
    序列
    Gly2-Pro686
    产品特性
    Recombinant Human cGMP-Dependent Protein Kinase 1 is produced by our Mammalian expression system and the target gene encoding Gly2-Pro686 is expressed with a 6His tag at the C-terminus.
    纯度
    > 80 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PRKG1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF,20 % glycerol, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    别名
    PRKG1 (PRKG1 产品)
    别名
    prkg1 Protein, zgc:63955 Protein, Pkgi Protein, cGk1 Protein, 1 Protein, PKG Protein, PRKG1B Protein, PRKGR1B Protein, cGK Protein, cGK 1 Protein, cGK1 Protein, cGKI Protein, cGKI-BETA Protein, cGKI-alpha Protein, CGKI Protein, cGKI-beta Protein, AW125416 Protein, Gm19690 Protein, Prkg1b Protein, Prkgr1b Protein, Prkg1beta Protein, protein kinase, cGMP-dependent, type Ia Protein, protein kinase, cGMP-dependent, type I Protein, protein kinase, cGMP-dependent, type 1 Protein, prkg1a Protein, PRKG1 Protein, prkg1 Protein, Prkg1 Protein
    背景

    Background: cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one protein kinase domain. PRKG1 is mainly expressed in the lung and placenta. PRKG1 acts as a key mediator of the nitric oxide (NO)/cGMP signaling pathway. PRKG1 can phosphorylate many proteins that regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-signaling pathway, and other processes involved in several aspects of the CNS like axon guidance, hippocampal and cerebellar learning, circadian rhythm, and nociception.

    Synonym: cGMP-Dependent Protein Kinase 1, cGK 1, cGK1, cGMP-Dependent Protein Kinase I, cGKI, PRKG1, PRKG1B, PRKGR1A, PRKGR1B

    分子量
    78.8 kDa
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