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Prostate Specific Antigen Protein (PSA) (AA 25-261) (His tag)

PSA 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318944
发货至: 中国
  • 抗原 See all Prostate Specific Antigen (PSA) 蛋白
    Prostate Specific Antigen (PSA)
    蛋白类型
    Recombinant
    产品特性
    AA 25-261
    宿主
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    资源
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    人细胞
    标记
    This Prostate Specific Antigen protein is labelled with His tag.
    原理
    Recombinant Human PSA/KLK3 Protein (aa 25-261, His Tag)
    序列
    Ile25-Pro261
    产品特性
    Recombinant Human Kallikrein-3/Prostate-specific antigen is produced by our Mammalian expression system and the target gene encoding Ile25-Pro261 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PSA 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHcl, 150 mM NaCl,1 mM CaCl2, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Prostate Specific Antigen (PSA)
    别名
    PSA/KLK3 (PSA 产品)
    别名
    APS Protein, KLK2A1 Protein, PSA Protein, hK3 Protein, KLK3 Protein, Klk1c10l2 Protein, RSGK-50 Protein, RSKG-50 Protein, rGK-3 Protein, Kal-3 Protein, Kal3 Protein, Klk3 Protein, AAP-S Protein, MP100 Protein, Psa Protein, R74825 Protein, goku Protein, kallikrein related peptidase 3 Protein, kallikrein 3 Protein, kallikrein 1-related peptidase C3 Protein, kallikrein B, plasma 1 Protein, aminopeptidase puromycin sensitive Protein, KLK3 Protein, Klk1c3 Protein, Klkb1 Protein, Npepps Protein
    背景

    Background: KLK3, also known as APS, is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

    Synonym: APS,Hk3,KLK2A1,PSA,Prostate-Specific Antigen, PSA, Gamma-Seminoprotein, Seminin, Kallikrein-3, P-30 Antigen, Semenogelase,

    分子量
    27.1 kDa
    UniProt
    P07288
    途径
    Complement System
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