PCBP1 Protein (His tag)
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- 抗原 See all PCBP1 蛋白
- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PCBP1 protein is labelled with His tag.
- 原理
- Recombinant Human PCBP1 Protein (His Tag)
- 序列
- Asp 2-Cys 356
- 产品特性
- A DNA sequence encoding the human PCBP1 (NP_006187.2) (Asp 2-Cys 356) was expressed, with a polyhistidine tag at the N-terminus.
- 纯度
- > 87 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PCBP1 蛋白
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Poly(rC) Binding Protein 1 (PCBP1) (AA 1-163) protein (His tag)
PCBP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Poly(rC) Binding Protein 1 (PCBP1) (AA 1-356) protein (GST tag)PCBP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) protein (GST tag)PCBP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Poly(rC) Binding Protein 1 (PCBP1) (AA 1-356) protein (Strep Tag)Crystallography grade PCBP1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Poly(rC) Binding Protein 1 (PCBP1) (AA 1-356) protein (Strep Tag)Crystallography grade PCBP1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Poly(rC) Binding Protein 1 (PCBP1) protein (Myc-DYKDDDDK Tag)PCBP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 500 mM NaCl, 20 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
- 别名
- PCBP1 (PCBP1 产品)
- 别名
- PCBP1 Protein, HNRPE1 Protein, HNRPX Protein, hnRNP-E1 Protein, hnRNP-X Protein, hnRNP E1 Protein, WBP17 Protein, [a]CP-1 Protein, alphaCP-1 Protein, RGD1561319 Protein, poly(rC) binding protein 1 Protein, poly(rC) binding protein 1 L homeolog Protein, poly(rC)-binding protein 1 Protein, PCBP1 Protein, pcbp1.L Protein, LOC100388387 Protein, Pcbp1 Protein
- 背景
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Background: Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. PCBP1 is widely expressed in many human tissues and involved in regulation of transcription, transportation process, and function of RNA molecules. PCBP1 plays a pivotal role in post-transcriptional regulation for RNA metabolism and RNA function in gene expression. PCBP1 acts as a negative regulator of CD44 variants splicing in HepG2 cells, and loss of PCBP1 in human hepatic tumor contributes to the formation of a metastatic phenotype.
Synonym: HEL-S-85,hnRNP-E1,hnRNP-X,HNRPE1,HNRPX
- 分子量
- 38.3 kDa
- NCBI登录号
- NP_006187
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