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PVRL4 Protein (Fc Tag)

PVRL4 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7320868
发货至: 中国
  • 抗原 See all PVRL4 蛋白
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 24
    • 7
    • 2
    • 1
    • 1
    • 1
    小鼠
    资源
    • 22
    • 4
    • 4
    • 3
    • 2
    • 1
    人细胞
    标记
    This PVRL4 protein is labelled with Fc Tag.
    原理
    Recombinant Mouse Nectin-4 (C-Fc)
    序列
    Gly31-Ser349
    产品特性
    Recombinant Mouse Poliovirus Receptor-Related Protein  4 is produced by our Mammalian expression system and the target gene encoding Gly31-Ser349 is expressed with a Fc tag at the C-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Biological Activity Comment
    Immobilized Recombinant Mouse Nectin-4 (C-6His)(Cat#PKSM041376) at 10μg/ml (100 μl/well) can bind Recombinant Mouse Nectin-4 (C-Fc)(Cat#PKSM041375). The ED50 of PKSM041375 is 0.75 ug/ml.
    Top Product
    Discover our top product PVRL4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    别名
    Nectin-4 (PVRL4 产品)
    别名
    PVRL4 Protein, si:ch211-155e24.1 Protein, 1200017F15Rik Protein, Prr4 Protein, RGD1559826 Protein, EDSS1 Protein, LNIR Protein, PRR4 Protein, nectin-4 Protein, nectin cell adhesion molecule 4 Protein, NECTIN4 Protein, nectin4 Protein, Nectin4 Protein
    背景

    Background: Nectin-4(PVRL4)isatypeItransmembraneglycoproteinwhichbelongstothenectinfamilyofIgsuperfamilyproteins.ItcontainstwoIg-likeC2-typedomainsandoneIg-likeV-typedomain.PVRL4seemstobeinvolvedincelladhesionthroughtrans-homophilicand-heterophilicinteractions,thelatterincludingspecificallyinteractionswithnectin-1.Itdoesnotactasreceptorforalpha-herpesvirusentryintocells.Itispredominantlyexpressedinplacenta,theembryoandbreastcarcinoma.Butitisnotdetectedinnormalbreastepithelium.Thesolubleformisproducedbyproteolyticcleavageatthecellsurface(shedding),probablybyADAM17.Mutationsinthisgenearethecauseofectodermaldysplasia-syndactylysyndrometype 1, an autosomal recessive disorder.

    Synonym: PVRL4, Nectin-4, Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4, PRR4, LNIR

    分子量
    61.4kDa
    UniProt
    Q8R007
    途径
    Cell-Cell Junction Organization
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