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PVRL4 Protein (AA 32-349) (His tag,AVI tag,Biotin)

PVRL4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6938938
发货至: 中国
  • 抗原 See all PVRL4 蛋白
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 32-349
    宿主
    • 23
    • 8
    • 2
    • 1
    • 1
    • 1
    资源
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    HEK-293 Cells
    标记
    This PVRL4 protein is labelled with His tag,AVI tag,Biotin.
    序列
    AA 32-349
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product PVRL4 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    别名
    Nectin-4 (PVRL4 产品)
    别名
    PVRL4 Protein, si:ch211-155e24.1 Protein, 1200017F15Rik Protein, Prr4 Protein, RGD1559826 Protein, EDSS1 Protein, LNIR Protein, PRR4 Protein, nectin-4 Protein, nectin cell adhesion molecule 4 Protein, NECTIN4 Protein, nectin4 Protein, Nectin4 Protein
    背景
    Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50 % , 49 % and 86 %o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
    分子量
    37.8 kDa
    NCBI登录号
    NP_112178
    途径
    Cell-Cell Junction Organization
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