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PLXDC1 Protein (His tag)

PLXDC1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318914
发货至: 中国
  • 抗原 See all PLXDC1 蛋白
    PLXDC1 (Plexin Domain Containing 1 (PLXDC1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 3
    资源
    • 4
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This PLXDC1 protein is labelled with His tag.
    原理
    Recombinant Human TEM7/PLXDC1 Protein (His Tag)
    序列
    Leu19-Thr426
    产品特性
    Recombinant Human Plexin Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr426 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PLXDC1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Threhalose, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    PLXDC1 (Plexin Domain Containing 1 (PLXDC1))
    别名
    TEM7/PLXDC1 (PLXDC1 产品)
    别名
    PLXDC1 Protein, TEM3 Protein, TEM7 Protein, 2410003I07Rik Protein, AI848450 Protein, Tem7 Protein, Arl12 Protein, plexin domain containing 1 Protein, PLXDC1 Protein, Plxdc1 Protein
    背景

    Background: Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).

    Synonym: Plexin Domain-Containing Protein 1, Tumor Endothelial Marker 3, Tumor Endothelial Marker 7, PLXDC1, TEM3, TEM7

    分子量
    46.5 kDa
    UniProt
    Q8IUK5
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