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PLXDC1 Protein (AA 19-426) (His tag)

PLXDC1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097619
发货至: 中国
  • 抗原 See all PLXDC1 蛋白
    PLXDC1 (Plexin Domain Containing 1 (PLXDC1))
    蛋白类型
    Recombinant
    产品特性
    AA 19-426
    宿主
    • 6
    • 3
    资源
    • 4
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This PLXDC1 protein is labelled with His tag.
    原理
    Recombinant Human Plexin Domain-Containing Protein 1/PLXDC1 (C-6His)
    序列
    LSPQPGAGHD EGPGSGWAAK GTVRGWNRRA RESPGHVSEP DRTQLSQDLG GGTLAMDTLP DNRTRVVEDN HSYYVSRLYG PSEPHSRELW VDVAEANRSQ VKIHTILSNT HRQASRVVLS FDFPFYGHPL RQITMATGGF IFMGDVIHRM LTATQYVAPL MANFNPGYSD NSTVVYFDNG TVFVVQWDHV YLQGWEDKGS FTFQAALHHD GRIVFAYKEI PMSVPEISSS QHPVKTGLSD AFMILNPSPD VPESRRRSIF EYHRIELDPS KVTSMSAVEF TPLPTCLQHR SCDACMSSDL TFNCSWCHVL QRCSSGFDRY RQEWMDYGCA QEAEGRMCED FQDEDHDSAS PDTSFSPYDG DLTTTSSSLF IDSLTTEDDT KLNPYAGGDG LQNNLSPKTK GTPVHLGTVD HHHHHH
    产品特性
    Recombinant Human Plexin Domain-Containing Protein 1/PLXDC1 produced by transfected human cells is a secreted protein with sequence (Leu19 Thr426) of human PLXDC1/TEM7 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PLXDC1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Threhalose, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    PLXDC1 (Plexin Domain Containing 1 (PLXDC1))
    别名
    tem7 (PLXDC1 产品)
    别名
    PLXDC1 Protein, TEM3 Protein, TEM7 Protein, 2410003I07Rik Protein, AI848450 Protein, Tem7 Protein, Arl12 Protein, plexin domain containing 1 Protein, PLXDC1 Protein, Plxdc1 Protein
    Sub Type
    Fusionprotein
    背景
    Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).
    Alternative Names: Plexin Domain-Containing Protein 1, Tumor Endothelial Marker 3, Tumor Endothelial Marker 7, PLXDC1, TEM3, TEM7
    分子量
    46.53 kDa
    UniProt
    Q8IUK5
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