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PDGFRA Protein (Fc Tag)

PDGFRA 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320624
发货至: 中国
  • 抗原 See all PDGFRA 蛋白
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    蛋白类型
    Recombinant
    宿主
    • 26
    • 7
    • 4
    • 1
    • 1
    小鼠
    资源
    • 13
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人细胞
    标记
    This PDGFRA protein is labelled with Fc Tag.
    原理
    Recombinant Mouse PDGFRa/CD140a Protein (Fc Tag)
    序列
    Leu25-Glu524
    产品特性
    Recombinant Mouse Platelet-derived growth factor receptor alpha is produced by our Mammalian expression system and the target gene encoding Leu25-Glu524 is expressed with a Fc tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PDGFRA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    别名
    PDGFRa/CD140a (PDGFRA 产品)
    别名
    AI115593 Protein, CD140a Protein, Pdgfr-2 Protein, APDGFR Protein, PDGFACE Protein, CD140A Protein, PDGFR-2 Protein, PDGFR2 Protein, RHEPDGFRA Protein, PDGFR Protein, PDGFR-A Protein, platelet derived growth factor receptor alpha Protein, platelet derived growth factor receptor, alpha polypeptide Protein, platelet-derived growth factor receptor, alpha polypeptide L homeolog Protein, platelet-derived growth factor receptor, alpha polypeptide Protein, PDGFRA Protein, Pdgfra Protein, pdgfra.L Protein
    背景

    Background: Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. PDGFRα and PDGFRβ are members of the class III RTK family. Inappropriate PDGFRα and PDGFRβ signaling has been linked to a number of proliferative disorders.

    Synonym: Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor,CD140 antigen-like family member A, Platelet-derived growth factor alpha receptor, CD140a, PDGFRA

    分子量
    83.2 kDa
    UniProt
    P26618
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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