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PHPT1 Protein (His tag)

PHPT1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317373
发货至: 中国
  • 抗原 See all PHPT1 蛋白
    PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 2
    • 1
    • 1
    • 1
    资源
    • 7
    • 4
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This PHPT1 protein is labelled with His tag.
    原理
    Recombinant Human PHPT1/PHP14 Protein (His Tag)
    序列
    Ala 2-Tyr 125
    产品特性
    A DNA sequence encoding the human PHPT1 (Q9NRX4-1) (Ala 2-Tyr 125) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product PHPT1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))
    别名
    PHPT1/PHP14 (PHPT1 产品)
    别名
    wu:fb50e08 Protein, zgc:101086 Protein, MGC131298 Protein, PHP14 Protein, CGI-202 Protein, HSPC141 Protein, RP11-216L13.10 Protein, bA216L13.10 Protein, 1700008C22Rik Protein, Php14 Protein, phosphohistidine phosphatase 1 Protein, phosphohistidine phosphatase 1 L homeolog Protein, 14 kDa phosphohistidine phosphatase-like Protein, LOC424401 Protein, phpt1 Protein, PHPT1 Protein, phpt1.L Protein, LOC100511240 Protein, Phpt1 Protein
    背景

    Background: PHPT1, also known as 14 kDa phosphohistidine phosphatase, phosphohistidine phosphatase 1, protein janus-A homolog, PHP14, is a cytoplasm protein which belongs to the janus family. PHPT1 / PHP14 is expressed abundantly in heart and skeletal muscle. Phosphatases are a diverse group of enzymes that regulate numerous cellular processes. Much of what is known relates to the tyrosine, threonine, and serine phosphatases, whereas the histidine phosphatases have not been studied as much. Protein histidine phosphorylation exists widely in vertebrates, and it plays important roles in signal transduction and other cellular functions. Protein histidine phosphorylation accounts for about 6% of the total protein phosphorylation in eukaryotic cells. The knowledge about eukaryotic PHPT (protein histidine phosphatase) is still very limited. To date, only one vertebrate PHPT has been discovered, and two crystal structures of human PHPT1 have been solved. PHPT1 / PHP14 can dephosphorylate a variety of proteins (e.g. ATP-citrate lyase and the beta-subunit of G proteins). A putative active site has been identified by its electrostatic character, ion binding, and conserved protein residues.

    Synonym: CGI-202;HEL-S-132P;HSPC141;PHP14

    分子量
    15.2 kDa
    途径
    Positive Regulation of Peptide Hormone Secretion
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