PDE1B Protein (GST tag,His tag)
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- 抗原 See all PDE1B 蛋白
- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This PDE1B protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human PDE1B Protein (His & GST Tag)
- 序列
- Met 1-Asp 536
- 产品特性
- A DNA sequence encoding the human PDE1B long isoform (Q01064-1) (Met 1-Asp 536) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 94 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PDE1B 蛋白
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phosphodiesterase 1B, Calmodulin-Dependent (PDE1B) (AA 437-536) protein (GST tag)
PDE1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
phosphodiesterase 1B, Calmodulin-Dependent (PDE1B) (AA 1-536) protein (Strep Tag)Crystallography grade PDE1B 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
phosphodiesterase 1B, Calmodulin-Dependent (PDE1B) (AA 1-535) protein (Strep Tag)Crystallography grade PDE1B 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
phosphodiesterase 1B, Calmodulin-Dependent (PDE1B) protein (Myc-DYKDDDDK Tag)PDE1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
- 别名
- PDE1B (PDE1B 产品)
- 别名
- 63kDa Protein, Pde1b1 Protein, PDE1B1 Protein, PDES1B Protein, Aop2 Protein, phosphodiesterase 1B, Ca2+-calmodulin dependent Protein, phosphodiesterase 1B Protein, Pde1b Protein, PDE1B Protein
- 背景
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Background: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, also known as Cam-PDE 1B and PDE1B, is a cytoplasm protein which belongs to the cyclic nucleotide phosphodiesterase family and PDE1 subfamily. Phosphodiesterase-10A (PDE10A), Phosphodiesterase-1B (PDE1B), Phosphodiesterase-4B (PDE4B), and Phosphodiesterase-4A (PDE4A) are important regulators of signal transduction in striatum due to their catalysis of cyclic AMP and cyclic GMP. PDE1B is highly expressed in the striatum. It binds two divalent metal cations per subunit. Site one of PDE1B may preferentially bind zinc ions, while site two of PDE1B has a preference for magnesium and/or manganese ions. PDE1B is a cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. It has a preference for cGMP as a substrate.
Synonym: PDE1B1;PDES1B
- 分子量
- 89.2 kDa
- 途径
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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