NPC2 Protein (His tag)
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- 抗原 See all NPC2 蛋白
- NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This NPC2 protein is labelled with His tag.
- 原理
- Recombinant Rat NPC2 Protein (His Tag)
- 序列
- Met1-Gly152
- 产品特性
- A DNA sequence encoding the rat Npc2 (CAD56199.1) (Met1-Gly152) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg protein as determined by the LAL method.
- Top Product
- Discover our top product NPC2 蛋白
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Niemann-Pick Disease, Type C2 (NPC2) (AA 1-151) protein (GST tag)
NPC2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Niemann-Pick Disease, Type C2 (NPC2) (AA 52-151) protein (GST tag)NPC2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Niemann-Pick Disease, Type C2 (NPC2) (AA 20-151) protein (His tag)Crystallography grade NPC2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Niemann-Pick Disease, Type C2 (NPC2) (AA 20-149) protein (His tag)Crystallography grade NPC2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Niemann-Pick Disease, Type C2 (NPC2) (AA 22-149), (full length) protein (His tag)NPC2 宿主: 犬 宿主: 酵母菌 Recombinant > 90 % ELISA
Niemann-Pick Disease, Type C2 (NPC2) (AA 22-149) protein (His tag)NPC2 宿主: 犬 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
- 别名
- NPC2 (NPC2 产品)
- 别名
- 2700012J19Rik Protein, AA408070 Protein, AU045843 Protein, HE1 Protein, EDDM1 Protein, re1 Protein, CE1 Protein, EPI-1 Protein, cb292 Protein, sb:cb292 Protein, NPC intracellular cholesterol transporter 2 Protein, Niemann-Pick disease, type C2 Protein, Npc2 Protein, NPC2 Protein, npc2 Protein
- 背景
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Background: Niemann-Pick Type C2 (NPC2) plays an important role in the regulation of intracellular cholesterol homeostasis via direct binding with free cholesterol. NPC2 is an intralysosomal protein that binds cholesterol in vitro. NPC2 is a small lysosomal glycoprotein that binds cholesterol with submicromolar affinity. Deficiency in NPC2 is the cause of Niemann-Pick type C2 disease, a fatal neurovisceral disorder characterized by accumulation of cholesterol in lysosomes.Niemann-Pick disease, type C2 (NPC2) protein is one of the most abundant components of the epididymal fluid and contains a functional cholesterol-binding site that can transfer cholesterol between membranes, it has been suggested for years that NPC2 could be involved in the regulation of cholesterol levels in spermatozoa during epididymal maturation.
Synonym: re1 Niemann-Pick disease type C2,NPC2
- 分子量
- 15.9 kDa
- 途径
- SARS-CoV-2 Protein Interactome
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