NPC1 Protein (His tag,DYKDDDDK Tag)
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- 抗原 See all NPC1 蛋白
- NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NPC1 protein is labelled with His tag,DYKDDDDK Tag.
- 原理
- Recombinant Human NPC1 Protein (His & FLAG Tag)
- 序列
- Arg372-Phe622
- 产品特性
- A DNA sequence encoding the human NPC1 (NP_000262.2) (Arg372-Phe622) was expressed with a N-terminal polyhistide-tagged FLAG tag at the N-terminus (his-FLAG).
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product NPC1 蛋白
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Niemann-Pick Disease, Type C1 (NPC1) (AA 151-250) protein (GST tag)
NPC1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Niemann-Pick Disease, Type C1 (NPC1) (AA 372-620) protein (His tag)Crystallography grade NPC1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
Niemann-Pick Disease, Type C1 (NPC1) (AA 372-621) protein (His tag)Crystallography grade NPC1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
Niemann-Pick Disease, Type C1 (NPC1) (AA 23-269) protein (His tag)Crystallography grade NPC1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
Niemann-Pick Disease, Type C1 (NPC1) (AA 854-1098) protein (His tag)Crystallography grade NPC1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
Niemann-Pick Disease, Type C1 (NPC1) (AA 23-269) protein (His tag)Crystallography grade NPC1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
Niemann-Pick Disease, Type C1 (NPC1) (AA 854-1076) protein (His tag)Crystallography grade NPC1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
Niemann-Pick Disease, Type C1 (NPC1) (AA 23-1278) protein (rho-1D4 tag)Crystallography grade NPC1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
Niemann-Pick Disease, Type C1 (NPC1) (AA 23-1277) protein (rho-1D4 tag)Crystallography grade NPC1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, Crys, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NPC1 (Niemann-Pick Disease, Type C1 (NPC1))
- 别名
- NPC1 (NPC1 产品)
- 别名
- NPC Protein, 9130221N23Rik Protein, Gm243 Protein, Cdig2 Protein, im:7149020 Protein, wu:fb53a12 Protein, wu:fc29a12 Protein, A430089E03Rik Protein, C85354 Protein, D18Ertd139e Protein, D18Ertd723e Protein, lcsd Protein, nmf164 Protein, spm Protein, NPC intracellular cholesterol transporter 1 Protein, NPC1 like intracellular cholesterol transporter 1 Protein, Niemann-Pick disease, type C1 Protein, Niemann-Pick C1 protein Protein, NPC1 Protein, Npc1l1 Protein, Npc1 Protein, npc1 Protein, LOC579887 Protein
- 背景
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Background: Niemann-Pick C1 (NPC1), a host receptor involved in the envelope glycoprotein (GP)-mediated entry of filoviruses into cells, is believed to be a major determinant of cell susceptibility to filovirus infection. Niemann-Pick C1 (NPC1), a membrane protein of lysosomes, is required for the export of cholesterol derived from receptor-mediated endocytosis of LDL.The NPC1 protein is a multipass transmembrane protein whose deficiency causes the autosomal recessive lipid storage disorder Niemann-Pick type C1. NPC1 localizes predominantly to late endosomes and has a dileucine motif located within a small cytoplasmic tail thought to target the protein to this location.Niemann-Pick disease Type C1 (NPC1) is a rare progressive neurodegenerative disorder caused by mutations in the NPC1 gene. On the cellular level NPC1 mutations lead to an accumulation of cholesterol and gangliosides.
Synonym: NPC
- 分子量
- 32 kDa
- NCBI登录号
- NP_000262
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