TRKB Protein (Fc Tag)
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- 抗原 See all TRKB (NTRK2) 蛋白
- TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This TRKB protein is labelled with Fc Tag.
- 原理
- Recombinant Rat TrkB/NTRK2 Protein (Fc Tag)
- 序列
- Met1-His429
- 产品特性
- A DNA sequence encoding the Rat NTRK2 (NP_036863) (Met1-His429) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 92 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product NTRK2 蛋白
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Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 32-430) protein (His tag)
NTRK2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 456-822) (Active) protein (GST tag)NTRK2 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 526-838) (Active) protein (His-GST)NTRK2 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 32-205) protein (His-IF2DI Tag)NTRK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (Active) protein (His tag)NTRK2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 1-477) protein (GST tag)NTRK2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 41-160) protein (GST tag)NTRK2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (Active) protein (His tag)NTRK2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) protein (His tag)NTRK2 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
- 别名
- TrkB/NTRK2 (NTRK2 产品)
- 别名
- trkb Protein, trkb-b Protein, xtrkb Protein, si:ch211-220b11.1 Protein, trkB2 Protein, NTRK2 Protein, ntrk2 Protein, gp145-trkb Protein, TRKB Protein, GP145-TrkB Protein, trk-B Protein, AI848316 Protein, C030027L06Rik Protein, Tkrb Protein, trkB Protein, RATTRKB1 Protein, TRKB1 Protein, Trk-B Protein, TrkB Protein, neurotrophic receptor tyrosine kinase 2 Protein, neurotrophic receptor tyrosine kinase 2 L homeolog Protein, neurotrophic tyrosine kinase, receptor, type 2b Protein, neurotrophic receptor tyrosine kinase 2 S homeolog Protein, neurotrophic tyrosine kinase, receptor, type 2 Protein, NTRK2 Protein, ntrk2.L Protein, ntrk2b Protein, ntrk2.S Protein, ntrk2 Protein, Ntrk2 Protein
- 背景
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Background: TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptors with intracellular tyrosine kinase activity. TrkB/NTRK2 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TrkB tyrosine kinase (TrkB) or NTRK2 is coupled to the Ras, Cdc42/Rac/RhoG, MAPK, PI3-K and PLCgamma signaling pathways. There are four members of the Trk family; TrkA, TrkB and TrkC and a related p75NTR receptor. Each family member binds different neurotrophins with varying affinities. TrkB/NTRK has highest affinity for brain-derived neurotrophic factor (BDNF) and is involved in neuronal plasticity, longterm potentiation and apoptosis of CNS neurons. Other neurotrophins include nerve growth factor(NGF), neurotrophin-3 and neurotrophin-4. TrkB/NTRK is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in TrkB/NTRK have been associated with obesity and mood disorders.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: NTRK2;Trkb
- 分子量
- 71.5 kDa
- NCBI登录号
- NP_036863
- 途径
- RTK signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport
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