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NELL2 Protein (His tag)

NELL2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 87 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317297
发货至: 中国
  • 抗原 See all NELL2 蛋白
    NELL2 (NEL-Like 2 (Chicken) (NELL2))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 2
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This NELL2 protein is labelled with His tag.
    原理
    Recombinant Human NELL2 Protein (His Tag)
    序列
    Met 1-Leu 816
    产品特性
    A DNA sequence encoding the human NELL2 (Q99435) (Met 1-Leu 816) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 87 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product NELL2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    NELL2 (NEL-Like 2 (Chicken) (NELL2))
    别名
    NELL2 (NELL2 产品)
    别名
    A330108N19Rik Protein, R75516 Protein, mel91 Protein, nel Protein, NRP2 Protein, nell2 Protein, wu:fj43h11 Protein, zgc:158375 Protein, neural EGFL like 2 L homeolog Protein, NEL-like 2 Protein, neural EGFL like 2 Protein, neural EGFL like 2a Protein, nell2.L Protein, Nell2 Protein, NELL2 Protein, nell2a Protein
    背景

    Background: OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.Immune CheckpointImmune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Synonym: NRP2

    分子量
    90.4 kDa
    UniProt
    Q99435
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