NELL2 Protein (His tag)
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- 抗原 See all NELL2 蛋白
- NELL2 (NEL-Like 2 (Chicken) (NELL2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This NELL2 protein is labelled with His tag.
- 原理
- Recombinant Human NELL2 Protein (His Tag)
- 序列
- Met 1-Leu 816
- 产品特性
- A DNA sequence encoding the human NELL2 (Q99435) (Met 1-Leu 816) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 87 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product NELL2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NELL2 (NEL-Like 2 (Chicken) (NELL2))
- 别名
- NELL2 (NELL2 产品)
- 别名
- A330108N19Rik Protein, R75516 Protein, mel91 Protein, nel Protein, NRP2 Protein, nell2 Protein, wu:fj43h11 Protein, zgc:158375 Protein, neural EGFL like 2 L homeolog Protein, NEL-like 2 Protein, neural EGFL like 2 Protein, neural EGFL like 2a Protein, nell2.L Protein, Nell2 Protein, NELL2 Protein, nell2a Protein
- 背景
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Background: OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.Immune CheckpointImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: NRP2
- 分子量
- 90.4 kDa
- UniProt
- Q99435
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