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NELL2 Protein (AA 22-238) (His tag)

NELL2 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant ~95 % WB, ELISA, MS, Neut
产品编号 ABIN2468886
发货至: 中国
  • 抗原 See all NELL2 蛋白
    NELL2 (NEL-Like 2 (Chicken) (NELL2))
    蛋白类型
    Recombinant
    产品特性
    AA 22-238
    宿主
    • 6
    • 1
    • 1
    小鼠
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This NELL2 protein is labelled with His tag.
    应用范围
    Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
    纯度
    ~95 %
    Top Product
    Discover our top product NELL2 蛋白
  • 应用备注
    This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 mM sodium phosphate, 10 mM Tris, 500 mM NaCl, 25 mM imidazole, 2 mM MgCl2, 10 % gycerol
    注意事项
    Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    储存条件
    -80 °C
    储存方法
    Store in working aliquots at -70 °C.
  • 抗原
    NELL2 (NEL-Like 2 (Chicken) (NELL2))
    别名
    NELL2 (NELL2 产品)
    别名
    A330108N19Rik Protein, R75516 Protein, mel91 Protein, nel Protein, NRP2 Protein, nell2 Protein, wu:fj43h11 Protein, zgc:158375 Protein, neural EGFL like 2 L homeolog Protein, NEL-like 2 Protein, neural EGFL like 2 Protein, neural EGFL like 2a Protein, nell2.L Protein, Nell2 Protein, NELL2 Protein, nell2a Protein
    背景
    NELL2 is a neuron-specific thrombospondin-1-like extracellular protein containing six epidermal growth factor-like domains (1). It is highly expressed in the hippocampus in vivo (2) and promotes survival of rat primary cultured neurons through activation of JNK and suppression of ERK (3). As ERK is required for the induction of hippocampal long term potentiation (LTP) and JNK appears to be inhibitory on LTP (4,5), it had been suggested that NELL2 may play a role in synaptic plasticity. More recently, NELL2 has been shown to promote differentiation of motor and sensory neurons and stimulates mitogenesis of dorsal root ganglia in chickens (6).
    分子量
    28 kDa (Calculated)
    基因ID
    54003
    OMIM
    2494290
    UniProt
    Q61220
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