MAG Protein (Fc Tag,ECD)
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- 抗原 See all MAG 蛋白
- MAG (Myelin Associated Glycoprotein (MAG))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This MAG protein is labelled with Fc Tag,ECD.
- 原理
- Recombinant Mouse MAG/Siglec-4a Protein (ECD, Fc Tag)
- 序列
- Met1-Pro516
- 产品特性
- A DNA sequence encoding the mouse Mag (NP_034888.1) (Met1-Pro516) was expressed with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product MAG 蛋白
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Myelin Associated Glycoprotein (MAG) (AA 20-516) protein (His tag)
MAG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Myelin Associated Glycoprotein (MAG) (AA 20-516) protein (His-Avi Tag,Biotin)MAG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Myelin Associated Glycoprotein (MAG) (AA 20-516) protein (His tag)MAG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Myelin Associated Glycoprotein (MAG) (AA 20-516) protein (Fc Tag)MAG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Myelin Associated Glycoprotein (MAG) (AA 1-626) protein (GST tag)MAG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myelin Associated Glycoprotein (MAG) (AA 119-208) protein (GST tag)MAG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myelin Associated Glycoprotein (MAG) (AA 20-516) protein (His tag)Crystallography grade MAG 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Myelin Associated Glycoprotein (MAG) (AA 20-516) protein (His tag)Crystallography grade MAG 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Myelin Associated Glycoprotein (MAG) (AA 20-626) protein (rho-1D4 tag)Crystallography grade MAG 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Myelin Associated Glycoprotein (MAG) (AA 20-626) protein (rho-1D4 tag)Crystallography grade MAG 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- MAG (Myelin Associated Glycoprotein (MAG))
- 别名
- MAG/Siglec-4a (MAG 产品)
- 别名
- GMA Protein, S-MAG Protein, SIGLEC-4A Protein, SIGLEC4A Protein, siglec-4 Protein, MAG Protein, Gma Protein, siglec-4a Protein, myelin associated glycoprotein Protein, myelin-associated glycoprotein Protein, MAG Protein, mag Protein, Mag Protein
- 背景
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Background: The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100 kDa localized in myelin sheaths of periaxonal Schwann cell and oligodendroglial membranes where it functions in glia-axon interactions. It appears to function both as a receptor for an axonal signal that promotes the differentiation, maintenance and survival of oligodendrocytes and as a ligand for an axonal receptor that is needed for the maintence of myelinated axons. MAG contains a carbohydrate epitope shared with other glycoconjugates that is a target antigen in autoimmune peripheral neuropathy associated with IgM gammopathy and has been implicated in a dying back oligodendrogliopathy in multiple sclerosis. MAG is considered as a transmembrane protein of both CNS and PNS myelin and it strongly inhibits neurite outgrowth in both developing cerebellar and adult dosal root ganglion neurons. In contrast, MAG promotes neurite outgrowth from newborn DRG neurons. Thus, MAG may be responsible for the lack of CNS nerve regeneration and may influce both temporally and spatially regeneration in the PNS.
Synonym: Myelin-Associated Glycoprotein,MAG,Siglec-4a
- 分子量
- 81.6 kDa
- NCBI登录号
- NP_034888
- 途径
- Neurotrophin Signaling Pathway
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