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MAPT Protein (His tag)

MAPT 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318057
发货至: 中国
  • 抗原 See all MAPT 蛋白
    MAPT (Microtubule-Associated Protein tau (MAPT))
    蛋白类型
    Recombinant
    宿主
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 5
    • 4
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This MAPT protein is labelled with His tag.
    原理
    Recombinant Human MAPT/Tau Protein (His Tag)
    序列
    Ala2-Leu352
    产品特性
    A DNA sequence encoding the mature form of human MAPT (NP_058525.1) (Ala2-Leu352) was expressed with a polyhistide tag at the N-terminus.
    纯度
    > 85 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MAPT 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    MAPT (Microtubule-Associated Protein tau (MAPT))
    别名
    MAPT/Tau (MAPT 产品)
    别名
    DDPAC Protein, FTDP-17 Protein, MAPTL Protein, MSTD Protein, MTBT1 Protein, MTBT2 Protein, PPND Protein, TAU Protein, AI413597 Protein, AW045860 Protein, Mtapt Protein, Tau Protein, RNPTAU Protein, pTau Protein, tau Protein, xtp Protein, MAPT Protein, PHF-tau Protein, slc6a6 Protein, taut Protein, wu:fc26e12 Protein, microtubule associated protein tau Protein, microtubule-associated protein tau Protein, microtubule associated protein tau S homeolog Protein, Microtubule-associated protein tau Protein, solute carrier family 6 (neurotransmitter transporter), member 6b Protein, MAPT Protein, Mapt Protein, mapt.S Protein, LOC5580230 Protein, CpipJ_CPIJ013260 Protein, tau Protein, slc6a6b Protein
    背景

    Background: MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs.

    Synonym: DDPAC,FTDP-17,MAPT,MAPTL,MSTD,MTBT1,MTBT2,PPND,PPP1R103,TAU

    分子量
    38.7 kDa
    NCBI登录号
    NP_058525
    途径
    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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