CD20 Protein (TRX tag)
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- 抗原 See all CD20 (MS4A1) 蛋白
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CD20 protein is labelled with TRX tag.
- 原理
- Recombinant Human CD20/MS4A1 Protein (TrxA Tag)
- 序列
- Ile 141-Ser 188
- 产品特性
- A DNA sequence encoding the human MS4A1 (NP_068769.2) (Ile141-Ser188) was expressed with a TrxA tag at the N-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MS4A1 蛋白
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Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 141-188) protein (His-Avi Tag)
MS4A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 141-188) protein (His-Avi Tag,Biotin)MS4A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein-VLPMS4A1 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein-VLP (Biotin)MS4A1 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) protein (GST tag)MS4A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein (His tag)MS4A1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) (Active) protein (His tag)MS4A1 宿主: 人 宿主: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 141-188) protein (His-IF2DI Tag)MS4A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 210-297) protein (GST tag)MS4A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) (AA 1-297) protein (Strep Tag)Crystallography grade MS4A1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 150 mM NaCl, 1 mM EDTA, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
- 别名
- CD20/MS4A1 (MS4A1 产品)
- 别名
- B1 Protein, Bp35 Protein, CD20 Protein, CVID5 Protein, LEU-16 Protein, MS4A2 Protein, S7 Protein, AA960661 Protein, Cd20 Protein, Ly-44 Protein, Ms4a2 Protein, MS4A1 Protein, bp35 Protein, cd20 Protein, ms4a2 Protein, leu-16 Protein, ms4a4c Protein, cd20-like Protein, membrane spanning 4-domains A1 Protein, membrane-spanning 4-domains, subfamily A, member 1 Protein, B-lymphocyte antigen CD20 Protein, MS4A1 Protein, Ms4a1 Protein, ms4a1 Protein, LOC101694281 Protein
- 背景
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Background: CD20 (membrane-spanning 4-domains; subfamily A; member 1); also known as MS4A1; is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed on all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells; but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. CD20 / MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5(CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency; hypogammaglobulinemia; recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range; but can be low.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: B1;Bp35;CD20;CVID5;LEU-16;MS4A1;MS4A2;S7
- 分子量
- 23.9 kDa
- NCBI登录号
- NP_068769
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