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LYPD3 Protein (His tag)

LYPD3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
产品编号 ABIN7320237
发货至: 中国
  • 抗原 See all LYPD3 products
    LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 5
    • 2
    • 1
    小鼠
    资源
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This LYPD3 protein is labelled with His tag.
    原理
    Recombinant Mouse LYPD3 Protein (His Tag)(Active)
    序列
    Met 1-His 287
    产品特性
    A DNA sequence encoding the N-terminal segment of mouse LYPD3 (NP_598504.1) (Met 1-His 287) was expressed, with a polyhistidine tag at the C-terminus.
    纯度
    > 92 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind recombinant human Galectin3 in a functional ELISA.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
    别名
    LYPD3 (LYPD3 产品)
    别名
    LYPD3 Protein, MGC139913 Protein, C4.4A Protein, 2310061G07Rik Protein, C4.4a Protein, LY6/PLAUR domain containing 3 Protein, Ly6/Plaur domain containing 3 Protein, LYPD3 Protein, Lypd3 Protein
    背景

    Background: Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4 and LYPD3, is a cell membrane protein which contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression

    Synonym: 2310061G07Rik;C4.4a

    分子量
    28 kDa
    NCBI登录号
    NP_598504
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