LYPD3 Protein (His tag)
-
- 抗原 See all LYPD3 products
- LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This LYPD3 protein is labelled with His tag.
- 原理
- Recombinant Human LYPD3 Protein (His Tag)(Active)
- 序列
- Leu31-His286
- 产品特性
- Recombinant Human Ly6/PLAUR Domain-Containing Protein 3 is produced by our Mammalian expression system and the target gene encoding Leu31-His286 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human LGALS3(Cat: PKSH032474) at 0.5μg/ml(100 μl/well) can bind Human LYPD3-His.
-
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 31-286) protein (His tag)
LYPD3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 33-287) protein (His tag)LYPD3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 1-346) protein (GST tag)LYPD3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
LY6/PLAUR Domain Containing 3 (LYPD3) (Active) protein (His tag)LYPD3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
LY6/PLAUR Domain Containing 3 (LYPD3) (AA 31-326) protein (His tag)Crystallography grade LYPD3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
- 别名
- LYPD3 (LYPD3 产品)
- 别名
- LYPD3 Protein, MGC139913 Protein, C4.4A Protein, 2310061G07Rik Protein, C4.4a Protein, LY6/PLAUR domain containing 3 Protein, Ly6/Plaur domain containing 3 Protein, LYPD3 Protein, Lypd3 Protein
- 背景
-
Background: Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR). LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.
Synonym: Ly6/PLAUR Domain-Containing Protein 3, GPI-Anchored Metastasis-Associated Protein C4.4A Homolog, Matrigel-Induced Gene C4 Protein, MIG-C4, LYPD3, C4.4A
- 分子量
- 27.9 kDa
- NCBI登录号
- NP_055215
-
