LGALS8 Protein (GST tag)
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- 抗原 See all LGALS8 蛋白
- LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This LGALS8 protein is labelled with GST tag.
- 原理
- Recombinant Human Galectin-8/LGALS8 Protein (GST Tag)(Active)
- 序列
- Met 1-Trp 317
- 产品特性
- A DNA sequence encoding human LGALS8 (AAF19370.1) (Met 1-Trp 317) was fused with the GST tag at the N-terminus.
- 纯度
- > 76 % as determined by reducing SDS-PAGE.
- Biological Activity Comment
- Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 0.2-1 μg/ml.
- Top Product
- Discover our top product LGALS8 蛋白
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Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 1-358) protein (GST tag)
LGALS8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 262-359) protein (GST tag)LGALS8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (Active) protein (GST tag)LGALS8 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 0.1 M NaCl, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))
- 别名
- Galectin-8/LGALS8 (LGALS8 产品)
- 别名
- LGALS8 Protein, 1200015E08Rik Protein, AI326142 Protein, D13Ertd524e Protein, Lgals-8 Protein, galectin-8 Protein, Gal-8 Protein, PCTA-1 Protein, PCTA1 Protein, Po66-CBP Protein, xgalectin-VIIIa Protein, galectin 8 Protein, lectin, galactose binding, soluble 8 Protein, lectin, galactoside binding soluble 8 S homeolog Protein, LGALS8 Protein, Lgals8 Protein, lgals8.S Protein
- 背景
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Background: Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state in order to maintain a molecular structure that is capable of showing lectin activity. This endogenous lectin widely expressed at sites of inflammation and tumour growth, has been postulated as an attractive immunosuppressive agent to restore immune cell tolerance and homeostasis in autoimmune and inflammatory settings. On the other hand, galectin-1 contributes to different steps of tumour progression including cell adhesion, migration and tumour-immune escape, suggesting that blockade of galectin-1 might result in therapeutic benefits in cancer. Several potential glycoprotein ligands for galectin-1 have been identified, including lysosome-associated membrane glycoproteins and fibronectin, laminin, as well as T-cell glycoproteins CD43 and CD45. Evidence points to Gal-1 and its ligands as one of the master regulators of such immune responses as T-cell homeostasis and survival, T-cell immune disorders, inflammation and allergies as well as host-pathogen interactions.
Synonym: Galectin-8, Gal-8, Po66 Carbohydrate-Binding Protein, Po66-CBP, Prostate Carcinoma Tumor Antigen 1, PCTA-1, LGALS8
- 分子量
- 62.7 kDa
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