Kallikrein 13 Protein (His tag)
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- 抗原 See all Kallikrein 13 (KLK13) 蛋白
- Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Kallikrein 13 protein is labelled with His tag.
- 原理
- Recombinant Human Kallikrein 13/KLK13 Protein (His Tag)(Active)
- 序列
- Met 1-Ile 262
- 产品特性
- A DNA sequence encoding the pro-form of human KLK13 (NP_056411.1) (Met 1-Ile 262) was expressed with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC (R&D Systems, Catalog # ES011). The specific activity is >200 pmoles/min/μg.(Activation description: The proenzyme needs to be activated by Lysyl-Endopeptidase for an activated form)
- Top Product
- Discover our top product KLK13 蛋白
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Kallikrein-Related Peptidase 13 (KLK13) (AA 1-277) protein (GST tag)
KLK13 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Kallikrein-Related Peptidase 13 (KLK13) (AA 179-277) protein (GST tag)KLK13 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))
- 别名
- Kallikrein 13/KLK13 (KLK13 产品)
- 别名
- KLK-L4 Protein, KLKL4 Protein, Egfbp-2 Protein, mGk-13 Protein, kallikrein related peptidase 13 Protein, kallikrein related-peptidase 13 Protein, KLK13 Protein, Klk13 Protein
- 背景
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Background: Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.
Synonym: Kallikrein-13, Kallikrein-Like Protein 4, KLK-L4, KLK13, KLKL4
- 分子量
- 28.4 kDa
- NCBI登录号
- NP_056411
- 途径
- Complement System
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