Intestinal Alkaline Phosphatase Protein (ALPI) (Fc Tag)
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- 抗原 See all Intestinal Alkaline Phosphatase (ALPI) 蛋白
- Intestinal Alkaline Phosphatase (ALPI)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Intestinal Alkaline Phosphatase protein is labelled with Fc Tag.
- 原理
- Recombinant Human Alkaline Phosphatase/ALPI Protein (Fc Tag)(Active)
- 序列
- Met 1-Asp 503
- 产品特性
- A DNA sequence encoding the mature form of human ALPI (P09923) (Met 1-Asp 503),without the pro peptide, was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 83 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to cleave a fluorogenic substrate, 4-Methylumbelliferyl phosphate (4-MUP).The specific activity is > 10,000 pmoles/min/μg.
- Top Product
- Discover our top product ALPI 蛋白
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Intestinal Alkaline Phosphatase (ALPI) (AA 74-162) protein (GST tag)
ALPI 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Intestinal Alkaline Phosphatase (ALPI) protein (Myc-DYKDDDDK Tag)ALPI 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Intestinal Alkaline Phosphatase (ALPI)
- 别名
- Alkaline Phosphatase/ALPI (ALPI 产品)
- 别名
- IAP Protein, Alp1 Protein, S51097 Protein, 2010001C14Rik Protein, Akp6 Protein, gIAP Protein, alpi Protein, im:7149588 Protein, si:ch211-262h13.1 Protein, wu:fa95f04 Protein, zgc:110794 Protein, ALPI Protein, Alpi Protein, alkaline phosphatase, intestinal Protein, alkaline phosphatase, intestinal, tandem duplicate 1 Protein, intestinal-type alkaline phosphatase Protein, ALPI Protein, Alpi Protein, alpi.1 Protein, LOC100724954 Protein
- 背景
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Background: Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR1, in which Tyr466 is changed to phenylalanine, can act in a dominant negative manner to inhibit phosphorylation of STAT2. These observations are consistent with a model in which IFNAR1 mediates the interaction between JAK kinases and the STAT transcription factors.
Synonym: IAP
- 分子量
- 79.5 kDa
- UniProt
- P09923
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