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IL-6 蛋白

This Recombinant IL-6 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7320602
发货至: 中国

Quick Overview for IL-6 蛋白 (ABIN7320602)

抗原

See all IL-6 (IL6) 蛋白
IL-6 (IL6) (Interleukin 6 (IL6))

蛋白类型

Recombinant

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小鼠

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by SDS-PAGE
  • 原理

    Recombinant Mouse Interleukin-6/IL-6 Protein

    序列

    Phe25-Thr211

    产品特性

    Recombinant Mouse Interleukin-6 is produced by our E.coli expression system and the target gene encoding Phe25-Thr211 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    Interleukin-6/IL-6

    背景

    Background: Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.

    Synonym: Interleukin-6, IL-6, B-Cell Hybridoma Growth Factor, Interleukin HP-1, Il6, Il-6

    分子量

    21.8 kDa

    UniProt

    P08505

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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