IL17 Receptor B Protein (His tag)
-
- 抗原 See all IL17 Receptor B (IL17RB) 蛋白
- IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This IL17 Receptor B protein is labelled with His tag.
- 原理
- Recombinant Human IL17BR/IL17RB Protein (His Tag)(Active)
- 序列
- Met 1-Gly289
- 产品特性
- A DNA sequence encoding the human IL17BR (NP_061195.2) (Met1-Gly289) was expressed with a C-terminal polyhistidine tag.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized human IL17BR-His at 10 μg/ml (100 μl/well) can bind human Fc-IL25 , The EC50 of human Fc-IL25 is 0.1-0.3 μg/ml.
- Top Product
- Discover our top product IL17RB 蛋白
-
Interleukin 17 Receptor B (IL17RB) (AA 18-292) protein (His tag)
IL17RB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor B (IL17RB) (AA 18-286) protein (His tag)IL17RB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor B (IL17RB) (AA 317-494) protein (His-IF2DI Tag)IL17RB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 17 Receptor B (IL17RB) (AA 18-117) protein (GST tag)IL17RB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 17 Receptor B (IL17RB) (Active) protein (His tag)IL17RB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
- 别名
- IL17BR/IL17RB (IL17RB 产品)
- 别名
- IL17RB Protein, CRL4 Protein, EVI27 Protein, IL17BR Protein, IL17RH1 Protein, Evi27 Protein, IL-17ER Protein, IL-17Rh1 Protein, Il17br Protein, interleukin 17 receptor B Protein, IL17RB Protein, Il17rb Protein
- 背景
-
Background: MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor missing in metastatic bladder carcinoma cell lines. MTSS1 is a prognostic indicator of disease-free survival in breast cancer patients and demonstrates the ability to play a role in governing the metastatic nature of breast cancer cells. MTSS1 may serve as a useful biomarker for the prediction of outcome of gastric cancer. The down-regulation of MTSS1 that may be caused by DNA methylation was also observed in many other types of cancer.Recent work proposed that MIM also potentiates Sonic hedgehog (Shh)-induced gene expression. MTSS1 as a multiple functional molecular player and has an important role in development, carcinogenesis and metastasis.
Synonym: CRL4,EVI27,IL17BR,IL17RH1
- 分子量
- 31.5 kDa
- NCBI登录号
- NP_061195
-
