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IL17 Receptor B Protein (AA 18-286) (His tag)

IL17RB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274912
发货至: 中国
  • 抗原 See all IL17 Receptor B (IL17RB) 蛋白
    IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
    蛋白类型
    Recombinant
    产品特性
    AA 18-286
    宿主
    • 13
    • 6
    • 2
    小鼠
    资源
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL17 Receptor B protein is labelled with His tag.
    原理
    Mouse IL-17RB Protein
    序列
    Arg18-Gly286
    产品特性
    Recombinant Mouse IL-17RB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg18-Gly286.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product IL17RB 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
    别名
    IL-17RB (IL17RB 产品)
    别名
    IL17RB Protein, CRL4 Protein, EVI27 Protein, IL17BR Protein, IL17RH1 Protein, Evi27 Protein, IL-17ER Protein, IL-17Rh1 Protein, Il17br Protein, interleukin 17 receptor B Protein, IL17RB Protein, Il17rb Protein
    背景
    Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.
    分子量
    30.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
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