IL17 Receptor B Protein (Fc Tag)
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- 抗原 See all IL17 Receptor B (IL17RB) 蛋白
- IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL17 Receptor B protein is labelled with Fc Tag.
- 原理
- Recombinant Human IL17BR/IL17RB Protein (Fc Tag)(Active)
- 序列
- Met 1-Gly289
- 产品特性
- A DNA sequence encoding the human IL17BR (NP_061195.2) (Met1-Gly289) was expressed with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized human IL17BR-Fc at 10μg/mL (100μL/well) can bind biotinylated human Fc-IL25.The EC50 of human Fc-IL25 is 4.5-10.4ng/mL.
- Top Product
- Discover our top product IL17RB 蛋白
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Interleukin 17 Receptor B (IL17RB) (AA 18-292) protein (His tag)
IL17RB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor B (IL17RB) (AA 18-286) protein (His tag)IL17RB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor B (IL17RB) (AA 317-494) protein (His-IF2DI Tag)IL17RB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 17 Receptor B (IL17RB) (AA 18-117) protein (GST tag)IL17RB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 17 Receptor B (IL17RB) (Active) protein (His tag)IL17RB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
- 别名
- IL17BR/IL17RB (IL17RB 产品)
- 别名
- IL17RB Protein, CRL4 Protein, EVI27 Protein, IL17BR Protein, IL17RH1 Protein, Evi27 Protein, IL-17ER Protein, IL-17Rh1 Protein, Il17br Protein, interleukin 17 receptor B Protein, IL17RB Protein, Il17rb Protein
- 背景
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Background: R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling. Activator of the beta-catenin signaling cascade leads to TCF-dependent gene activation. Action both in the canonical Wnt / beta- catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled / LRP receptors. Probably also acts as a ligand for frizzled and LRP receptors. The encoding gene Rspo2 was identified as a novel common integration site for the mouse mammary tumor virus in viral induced mouse mammary tumors. Rspo2 and Rspo2 / Wnt1 tumors contained many spindle cells, consistent with an epithelial-mesenchymal transformation phenotype. When Rspo2 and Rspo2 / Wnt1 tumor cells were transferred into naive mice, they exhibited greater metastatic activity than cells derived from Wnt1 tumors.
Synonym: CRL4,EVI27,IL17BR,IL17RH1
- 分子量
- 56.9 kDa
- NCBI登录号
- NP_061195
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