IL17RA Protein (His tag)
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- 抗原 See all IL17RA 蛋白
- IL17RA (Interleukin 17 Receptor A (IL17RA))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This IL17RA protein is labelled with His tag.
- 原理
- Recombinant Rat IL17RA Protein (His Tag)(Active)
- 序列
- Met1-Pro320
- 产品特性
- A DNA sequence encoding the rat IL17RA (NP_001101353.2) (Met1-Pro320) was expressed, fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- 1. Measured by its binding ability in a functional ELISA. Immobilized rat IL17RA-His at 10 μg/ml (100 μl/well) can bind biotinylated human IL17A, The EC50 of biotinylated human IL17A is 5-11.8 ng/ml.2.Measured by its binding ability in a functional ELISA. Immobilized mouse IL17a at 10 μg/ml (100 μl/well) can bind rat IL17RA-His, The EC50 of rat IL17RA-His is 0.44-1.02 μg/mL.
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- Discover our top product IL17RA 蛋白
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Interleukin 17 Receptor A (IL17RA) (AA 32-322) protein (Fc Tag)
IL17RA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor A (IL17RA) protein (Fc-Avi Tag,Biotin)IL17RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 17 Receptor A (IL17RA) (AA 33-320) protein (Fc Tag)IL17RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor A (IL17RA) protein (His-Avi Tag,Biotin)IL17RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin 17 Receptor A (IL17RA) (AA 33-320) protein (His tag)IL17RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor A (IL17RA) (AA 33-320) (Active) protein (Fc Tag,AVI tag,Biotin)IL17RA 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Interleukin 17 Receptor A (IL17RA) (AA 33-132) protein (GST tag)IL17RA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 17 Receptor A (IL17RA) (Active) protein (His tag)IL17RA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Interleukin 17 Receptor A (IL17RA) (Active) protein (Fc Tag)IL17RA 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 17 Receptor A (IL17RA) (AA 33-320) protein (His tag)Crystallography grade IL17RA 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL17RA (Interleukin 17 Receptor A (IL17RA))
- 别名
- IL17RA (IL17RA 产品)
- 别名
- IL17R Protein, CANDF5 Protein, CD217 Protein, CDw217 Protein, IL-17RA Protein, hIL-17R Protein, Il17r Protein, AW538159 Protein, Cdw217 Protein, VDw217 Protein, interleukin 17 receptor A Protein, IL17RA Protein, Il17ra Protein
- 背景
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Background: Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor which binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
Synonym: IL17RA
- 分子量
- 34.1 kDa
- NCBI登录号
- NP_001101353
- 途径
- SARS-CoV-2 Protein Interactome
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