IL13RA2 Protein (His tag)
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- 抗原 See all IL13RA2 蛋白
- IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This IL13RA2 protein is labelled with His tag.
- 原理
- Recombinant Rat IL13RA2/CD213A2 Protein (His Tag)(Active)
- 序列
- Met1-Lys336
- 产品特性
- A DNA sequence encoding the rat IL13RA2 (Q8VHK6) (Met1-Lys336) was expressed, fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 85 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- Measured by its ability to inhibit IL13-dependent proliferation of TF-1 human erythroleukemic cells.The ED50 for this effect is typically 0.005-0.03 μg/mL.
- Top Product
- Discover our top product IL13RA2 蛋白
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Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-342) protein (Fc Tag)
IL13RA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-343) (Active) protein (His tag)IL13RA2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-343) (Active) protein (Fc Tag)IL13RA2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-343) (Active) protein (FITC,His tag)IL13RA2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-126) protein (GST tag)IL13RA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 13 Receptor, alpha 2 (IL13RA2) (Active) protein (His tag,Fc Tag)IL13RA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (Active) protein (Fc Tag)IL13RA2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (Active) protein (His tag)IL13RA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-343) protein (His tag)Crystallography grade IL13RA2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 22-334) protein (His tag)Crystallography grade IL13RA2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))
- 别名
- IL13RA2/CD213A2 (IL13RA2 产品)
- 别名
- il-13ra2 Protein, sb:cb602 Protein, si:dkeyp-110c7.6 Protein, CD213A2 Protein, CT19 Protein, IL-13R Protein, IL13BP Protein, CD213a2 Protein, IL-13R-alpha-2 Protein, IL13RA2 Protein, interleukin 13 receptor, alpha 2 Protein, interleukin 13 receptor subunit alpha 2 Protein, interleukin 13 receptor subunit alpha 2 S homeolog Protein, il13ra2 Protein, IL13RA2 Protein, il13ra2.S Protein, Il13ra2 Protein
- 背景
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Background: Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.
Synonym: IL13R;IL13RA2
- 分子量
- 37.9 kDa
- UniProt
- Q8VHK6
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