IL13RA2 Protein (AA 27-343) (Fc Tag)
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- 抗原 See all IL13RA2 蛋白
- IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 27-343
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL13RA2 protein is labelled with Fc Tag.
- 产品特性
- Human IL-13 R alpha 2 Protein, Fc Tag (MALS verified)
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product IL13RA2 蛋白
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Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-342) protein (Fc Tag)
IL13RA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-343) (Active) protein (His tag)IL13RA2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-343) (Active) protein (FITC,His tag)IL13RA2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-126) protein (GST tag)IL13RA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 13 Receptor, alpha 2 (IL13RA2) (Active) protein (His tag,Fc Tag)IL13RA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (Active) protein (His tag)IL13RA2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (Active) protein (Fc Tag)IL13RA2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (Active) protein (His tag)IL13RA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 27-343) protein (His tag)Crystallography grade IL13RA2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 13 Receptor, alpha 2 (IL13RA2) (AA 22-334) protein (His tag)Crystallography grade IL13RA2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 应用备注
- MALS verified
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))
- 别名
- IL-13 R alpha 2 (IL13RA2 产品)
- 别名
- il-13ra2 Protein, sb:cb602 Protein, si:dkeyp-110c7.6 Protein, CD213A2 Protein, CT19 Protein, IL-13R Protein, IL13BP Protein, CD213a2 Protein, IL-13R-alpha-2 Protein, IL13RA2 Protein, interleukin 13 receptor, alpha 2 Protein, interleukin 13 receptor subunit alpha 2 Protein, interleukin 13 receptor subunit alpha 2 S homeolog Protein, il13ra2 Protein, IL13RA2 Protein, il13ra2.S Protein, Il13ra2 Protein
- 背景
- Interleukin-13 receptor subunit alpha-2 is also known as IL13Rα2, IL13Ra2 cluster of differentiation 213A2, CD213A2, CT19, IL-13R, IL13BP, and is a membrane bound protein that in humans is encoded by the IL13RA2 gene. IL13Rα2 is closely related to IL13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however able to regulate the effects of both IL13 and IL4, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13. IL13Rα2 is a component of the cell surface receptors, however, the majority exists in intracellular pools and in soluble form, and thus plays an opposite role as a potent IL13 antagonist compared with IL13Rα1. It also functions as an inhibitor of IL4-dependent pathway probably through the physical interaction between the short intracellular domain of and cytoplasmic domain of IL13Rα2 and the IL4Rα chain. In spite of the failed STAT signaling function, IL13Rα2 dose induce TGF-beta production and fibrosis. Additionally, IL13Rα2has been reported to be abundantly and specifically overexpressed in glioblastoma multiforme.
- 分子量
- 63.5 kDa
- NCBI登录号
- NP_000631
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