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IL1RL1 Protein (His tag)

IL1RL1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320553
发货至: 中国
  • 抗原 See all IL1RL1 蛋白
    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
    蛋白类型
    Recombinant
    宿主
    • 20
    • 10
    小鼠
    资源
    • 14
    • 5
    • 5
    • 3
    • 2
    • 1
    人细胞
    标记
    This IL1RL1 protein is labelled with His tag.
    原理
    Recombinant Mouse IL1RL1/ST2 Protein (His Tag)
    序列
    Ser27-Ala337
    产品特性
    Recombinant Mouse Interleukin-1 receptor-like 1 is produced by our Mammalian expression system and the target gene encoding Ser27-Ala337 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL1RL1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
    别名
    IL1RL1/ST2 (IL1RL1 产品)
    别名
    DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein
    背景

    Background: ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.

    Synonym: Interleukin-1 receptor-like 1, Lymphocyte antigen 84, Protein ST2, Protein T1, Il1rl1, DER4, Fit-1, IL-1 R4, IL-1RL1, IL-33R, Ly84, ST2L, ST2V, suppression of tumorigenicity 2

    分子量
    36.6 kDa
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