IL1RL1 Protein (AA 1-328, Isoform 2) (Fc Tag)
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- 抗原 See all IL1RL1 蛋白
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Isoform 2, AA 1-328
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL1RL1 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Binds to human IL-33.
- 交叉反应
- 人
- 产品特性
- Signal peptide and the sequence of isoform 2 of human ST2 (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >90 % (SDS-PAGE)
- 过滤
- 0.2 μm filtered
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1RL1 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Interacts with human IL-33.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in PBS, pH 7.2.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - 有效期
- 3 months
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- 抗原
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- 别名
- ST2 (IL1RL1 产品)
- 别名
- DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein
- 背景
- The ST2 (Interleukin-1 receptor-like 1, Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
- 分子量
- ~90kDa (SDS-PAGE)
- UniProt
- Q01638
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