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IL1RAP Protein (His tag,Fc Tag)

IL1RAP 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318595
发货至: 中国
  • 抗原 See all IL1RAP 蛋白
    IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
    蛋白类型
    Recombinant
    宿主
    • 19
    • 5
    • 1
    资源
    • 13
    • 5
    • 4
    • 2
    • 1
    人细胞
    标记
    This IL1RAP protein is labelled with His tag,Fc Tag.
    原理
    Recombinant Human IL-1RAcP/IL1R3 Protein (Fc & His Tag)
    序列
    Ser21-Gln356
    产品特性
    Recombinant Human Interleukin-1 Receptor Accessory Protein is produced by our Mammalian expression system and the target gene encoding Ser21-Gln356 is expressed with a Fc, 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL1RAP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
    别名
    IL-1RAcP/IL1R3 (IL1RAP 产品)
    别名
    IL1RAP Protein, il-1racp Protein, il-racp Protein, il1r3 Protein, C3orf13 Protein, IL-1RAcP Protein, IL1R3 Protein, 6430709H04Rik Protein, AI255955 Protein, AV239853 Protein, IL-1RAcp Protein, Il1racpb Protein, interleukin 1 receptor accessory protein Protein, IL1RAP Protein, il1rap Protein, il-1racp Protein, Il1rap Protein
    背景

    Background: Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.

    Synonym: Interleukin-1 Receptor Accessory Protein, IL-1 Receptor Accessory Protein, IL-1RAcP, Interleukin-1 Receptor 3, IL-1R-3, IL-1R3, IL1RAP, C3orf13, IL1R3

    分子量
    39.7 kDa
    UniProt
    Q9NPH3
    途径
    NF-kappaB Signaling, Growth Factor Binding
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