IFNGR2 Protein (His tag)
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- 抗原 See all IFNGR2 蛋白
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
- 蛋白类型
- Recombinant
- 宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This IFNGR2 protein is labelled with His tag.
- 原理
- Recombinant Mouse IFNGR2 Protein (His Tag)
- 序列
- Met 1-Val 243
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse IFNGR2 (NP_032364.1) (Met 1-Val 243) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 97 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product IFNGR2 蛋白
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Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) (AA 28-127) protein (GST tag)
IFNGR2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) (AA 1-337) protein (GST tag)IFNGR2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) protein (Myc-DYKDDDDK Tag)IFNGR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
- 别名
- IFNGR2 (IFNGR2 产品)
- 别名
- Ifgr2 Protein, Ifgt Protein, AF-1 Protein, IFGR2 Protein, IFNGT1 Protein, interferon gamma receptor 2 Protein, Ifngr2 Protein, IFNGR2 Protein, LOC487739 Protein
- 背景
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Background: Interferon gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. IFNGR2 is a component of the IFNgamma receptor complex along with the IFNgammaR alpha chain (IFNGR1), and is a new Bax suppressor. The C-terminal fragment (cytoplasmic domain) of IFNgammaR2 is expressed in human cancer cell lines of megakaryocytic cancer (DAMI), breast cancer (MDA-MD-468), and prostate cancer (PC3 cells). The Th1 cytokine IFNgamma, acting through its heterodimeric receptors, IFNgammaR1 and IFNgammaR2, in the induction/proliferation of Th1 cells, might suppress the Th2 responses that may underlie atopic asthma. IFNGR2 has always been seen as a key mechanism for shielding T lymphocytes from the antiproliferative effects of the IFNgamma-signal transducer and activator of transcription 1 (STAT1) pathway.
Synonym: Ifgr2,Ifgt
- 分子量
- 26.7 kDa
- NCBI登录号
- NP_032364
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