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IFNGR2 Protein (AA 28-247)

IFNGR2 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2017972
发货至: 中国
  • 抗原 See all IFNGR2 蛋白
    IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 28-247
    宿主
    • 7
    • 1
    资源
    • 4
    • 2
    • 2
    CHO Cells
    产品特性
    ED50 < 0.1 μg/mL, measured in a cell cytotoxicity assay using HT-29 (HTB-38) cells in the presence of 1 ng/mL human IFN-gamma.
    纯度
    > 95 % as analyzed by SDS-PAGE.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product IFNGR2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Human IFN-gamma Receptor II remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human IFN-gamma Receptor II should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
    Abstract
    IFNGR2 产品
    别名
    Ifgr2 Protein, Ifgt Protein, AF-1 Protein, IFGR2 Protein, IFNGT1 Protein, interferon gamma receptor 2 Protein, Ifngr2 Protein, IFNGR2 Protein, LOC487739 Protein
    背景
    IFN-gamma Receptor II, also known as IFNGR2 and IFNGT1, is a transmembrane protein belonging to the type II cytokine receptor family. IFNGR2 is a non-ligand-binding beta chain of the IFN-gamma receptor. It is an integral part of the IFN-gamma signaling transduction pathway and is likely to interact with GAF, JAK1 and JAK2. Defects in IFNGR2 are a cause of autosomal recessive Mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.
    Synonyms: IFNGR2, IFNGT1
    分子量
    38-40 kDa, observed by reducing SDS-PAGE.
    UniProt
    P38484
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