ICAM2 Protein (Fc Tag)
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- 抗原 See all ICAM2 蛋白
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This ICAM2 protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse ICAM-2/CD102 Protein (Fc Tag)(Active)
- 序列
- Met 1-Gln 222
- 产品特性
- A DNA sequence encoding the mouse ICAM2 (NP_034624.1) extracellular domain (Met 1-Gln 222) was fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 93 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. When cells are added to mouse ICAM2 coated plates (12.5 μg/ml, 100 μl/well), approximately 25-40% will adhere specifically.
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- Discover our top product ICAM2 蛋白
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Intercellular Adhesion Molecule 2 (ICAM2) protein (Fc Tag)
ICAM2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Intercellular Adhesion Molecule 2 (ICAM2) (AA 25-223) protein (His tag)ICAM2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Intercellular Adhesion Molecule 2 (ICAM2) (AA 1-275) protein (GST tag)ICAM2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Intercellular Adhesion Molecule 2 (ICAM2) (Active) proteinICAM2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Intercellular Adhesion Molecule 2 (ICAM2) (AA 25-223) protein (His tag)Crystallography grade ICAM2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Intercellular Adhesion Molecule 2 (ICAM2) (AA 23-222) protein (His tag)Crystallography grade ICAM2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Intercellular Adhesion Molecule 2 (ICAM2) (AA 25-275) protein (rho-1D4 tag)Crystallography grade ICAM2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Intercellular Adhesion Molecule 2 (ICAM2) (AA 23-277) protein (rho-1D4 tag)Crystallography grade ICAM2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris-Citric acid, 150 mM NaCl, pH 5.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- 别名
- ICAM-2/CD102 (ICAM2 产品)
- 别名
- ICAM2 Protein, CD102 Protein, Icam-2 Protein, Ly-60 Protein, intercellular adhesion molecule 2 Protein, LOC506088 Protein, ICAM2 Protein, LOC616254 Protein, LOC100140873 Protein, Icam2 Protein
- 背景
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Background: Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains, and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As a second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Synonym: Intercellular adhesion molecule 2, Icam2, ICAM-2, Lymphocyte function-associated AG-1 counter-receptor, CD102, Icam-2, CD102 antigen,Ly-60
- 分子量
- 50 kDa
- NCBI登录号
- NP_034624
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