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ITM2B Protein (His tag)

ITM2B 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318631
发货至: 中国
  • 抗原 See all ITM2B 蛋白
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This ITM2B protein is labelled with His tag.
    原理
    Recombinant Human ITM2B Protein (His Tag)
    序列
    Tyr76-Ser266
    产品特性
    Recombinant Human Integral Membrane Protein 2B is produced by our Mammalian expression system and the target gene encoding Tyr76-Ser266 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ITM2B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    别名
    ITM2B (ITM2B 产品)
    别名
    ABRI Protein, BRI Protein, BRI2 Protein, BRICD2B Protein, E25B Protein, E3-16 Protein, FBD Protein, imBRI2 Protein, AI256040 Protein, Bri Protein, Bri2 Protein, Bricd2b Protein, D14Sel6 Protein, E25BMM Protein, itm2b Protein, zgc:55770 Protein, zgc:85688 Protein, wu:fc05f02 Protein, MGC52745 Protein, MGC76131 Protein, ITM2B Protein, itm2bl Protein, wu:fb94b03 Protein, zgc:64142 Protein, integral membrane protein 2B Protein, integral membrane protein 2Ba Protein, integral membrane protein 2B L homeolog Protein, integral membrane protein 2b Protein, integral membrane protein 2Bb Protein, ITM2B Protein, Itm2b Protein, itm2ba Protein, itm2b.L Protein, itm2b Protein, itm2bb Protein
    背景

    Background: Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina.

    Synonym: Integral Membrane Protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane Protein BRI, Bri, ITM2B, BRI, BRI2

    分子量
    23.3 kDa
    UniProt
    Q9Y287
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