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ITM2B Protein (AA 76-266) (His tag)

ITM2B 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN2115428
发货至: 中国
  • 抗原 See all ITM2B 蛋白
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    蛋白类型
    Recombinant
    产品特性
    AA 76-266
    宿主
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This ITM2B protein is labelled with His tag.
    原理
    Recombinant Human Integral Membrane Protein 2B/ITM2B/imBRI2 (C-6His)
    序列
    YKYFALQPDD VYYCGIKYIK DDVILNEPSA DAPAALYQTI EENIKIFEEE EVEFISVPVP EFADSDPANI VHDFNKKLTA YLDLNLDKCY VIPLNTSIVM PPRNLLELLI NIKAGTYLPQ SYLIHEHMVI TDRIENIDHL GFFIYRLCHD KETYKLQRRE TIKGIQKREA SNCFAIRHFE NKFAVETLIC SVDHHHHHH
    产品特性
    Recombinant Human Integral Membrane Protein 2B/ITM2B is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Tyr76-Ser266) of Human ITM2B fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ITM2B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    别名
    ITM2B (ITM2B 产品)
    别名
    ABRI Protein, BRI Protein, BRI2 Protein, BRICD2B Protein, E25B Protein, E3-16 Protein, FBD Protein, imBRI2 Protein, AI256040 Protein, Bri Protein, Bri2 Protein, Bricd2b Protein, D14Sel6 Protein, E25BMM Protein, itm2b Protein, zgc:55770 Protein, zgc:85688 Protein, wu:fc05f02 Protein, MGC52745 Protein, MGC76131 Protein, ITM2B Protein, itm2bl Protein, wu:fb94b03 Protein, zgc:64142 Protein, integral membrane protein 2B Protein, integral membrane protein 2Ba Protein, integral membrane protein 2B L homeolog Protein, integral membrane protein 2b Protein, integral membrane protein 2Bb Protein, ITM2B Protein, Itm2b Protein, itm2ba Protein, itm2b.L Protein, itm2b Protein, itm2bb Protein
    背景
    Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina.
    Synonyms: Integral Membrane Protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane Protein BRI, Bri, ITM2B, BRI, BRI2
    分子量
    23.3 kDa
    UniProt
    Q9Y287
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