HTRA2 Protein (His tag)
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- 抗原 See all HTRA2 蛋白
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This HTRA2 protein is labelled with His tag.
- 原理
- Recombinant Human HtrA2/Omi Protein (His Tag)
- 序列
- Ala134-Glu458
- 产品特性
- Recombinant Human High Temperature Requirement Protein-2 is produced by our Mammalian expression system and the target gene encoding Ala134-Glu458 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product HTRA2 蛋白
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HtrA Serine Peptidase 2 (HTRA2) (full length) protein (His tag)
HTRA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
HtrA Serine Peptidase 2 (HTRA2) (AA 133-358) protein (His tag)HTRA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) protein (His tag)HTRA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
HtrA Serine Peptidase 2 (HTRA2) (AA 359-458) protein (GST tag)HTRA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) protein (rho-1D4 tag)Crystallography grade HTRA2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) protein (rho-1D4 tag)Crystallography grade HTRA2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 7.5.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- 别名
- HtrA2/Omi (HTRA2 产品)
- 别名
- CG8464 Protein, DmHtrA2 Protein, Dmel\\CG8464 Protein, HtrA2/Omi Protein, Omi Protein, dOmi Protein, domi Protein, htrA2 Protein, omi Protein, HTRA2 Protein, PRSS25 Protein, OMI Protein, PARK13 Protein, AI481710 Protein, Prss25 Protein, mnd2 Protein, HTRA2-related serine protease Protein, HtrA serine peptidase 2 Protein, HtrA2 Protein, HTRA2 Protein, htra2 Protein, Htra2 Protein
- 背景
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Background: High temperature requirement protein A2(HTRA2) is a single-pass membrane protein .It contains 1 PDZ (DHR) domain and belongs to the peptidase S1C family. HtrA2 can be released from the mitochondria during apoptosis and uses its four most N-terminal amino acids to mimic a caspase and be recruited by IAP caspase inhibitors such as XIAP and CIAP1/2. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. The protein cleaves THAP5 and promotes its degradation during apoptosis.
Synonym: Serine protease HTRA2, mitochondrial,High temperature requirement protein A2,HtrA2,Omi stress-regulated endoprotease,Serine protease 25,Serine proteinase OMI,HTRA2,OMI, PRSS25
- 分子量
- 36.0 kDa
- UniProt
- O43464
- 途径
- Positive Regulation of Endopeptidase Activity
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