HDAC8 Protein (GST tag)
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- 抗原 See all HDAC8 蛋白
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This HDAC8 protein is labelled with GST tag.
- 原理
- Recombinant Human HDAC8/HDACL1 Protein (GST Tag)
- 序列
- Met 1-Val 377
- 产品特性
- A DNA sequence encoding the full length of human HDAC8 isoform 1 (NP_060956.1) (Met 1-Val 377) was expressed, fused with the GST tag at the C-terminus.
- 纯度
- > 88 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HDAC8 蛋白
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Histone Deacetylase 8 (HDAC8) (AA 1-377) protein (GST tag)
HDAC8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Histone Deacetylase 8 (HDAC8) (AA 1-100) protein (GST tag)HDAC8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Histone Deacetylase 8 (HDAC8) protein (His tag)HDAC8 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
Histone Deacetylase 8 (HDAC8) (AA 1-377) protein (Strep Tag)Crystallography grade HDAC8 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Histone Deacetylase 8 (HDAC8) (AA 1-377) protein (Strep Tag)Crystallography grade HDAC8 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Histone Deacetylase 8 (HDAC8) (AA 1-377), (full length) protein (His-SUMO Tag)HDAC8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 10 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- 别名
- HDAC8/HDACL1 (HDAC8 产品)
- 别名
- HD8 Protein, CDLS5 Protein, HDACL1 Protein, MRXS6 Protein, RPD3 Protein, WTS Protein, 2610007D20Rik Protein, RGD1562895 Protein, wu:fd19a02 Protein, zgc:66196 Protein, ATHDA8 Protein, HDA8 Protein, HISTONE DEACETYLASE 8 Protein, T27G7.14 Protein, T27G7_14 Protein, histone deacetylase 8 Protein, histone deacetylase 8 Protein, histone deacetylase 8 L homeolog Protein, CC1G_05302 Protein, hdac8 Protein, HDAC8 Protein, Hdac8 Protein, hdac8.L Protein, HDA08 Protein
- 背景
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Background: Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein which belongs to the histone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzymes implicated in transcriptional regulation by affecting the acetylation state of core histones in the nucleus of cells. HDAC8 / HDACL1 is weakly expressed in most tissues. It expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney. HDAC8 / HDACL1 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones ( H2A, H2B, H3 and H4 ). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC8 / HDACL1 may play a role in smooth muscle cell contractility. HDAC8 / HDACL1 may be a potential drug target for neuroblastoma differentiation therapy using selective inhibitors, avoiding unspecific side effects.
Synonym: CDA07;CDLS5;HD8;HDACL1;MRXS6;RPD3;WTS
- 分子量
- 68 kDa
- NCBI登录号
- NP_060956
- 途径
- Cellular Glucan Metabolic Process
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