HEPACAM Protein (His tag)
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- 抗原 See all HEPACAM 蛋白
- HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This HEPACAM protein is labelled with His tag.
- 原理
- Recombinant Human HEPACAM Protein (His Tag)
- 序列
- Val34-Ser240
- 产品特性
- Recombinant Human Hepatocyte Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Val34-Ser240 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HEPACAM 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
- 别名
- HEPACAM (HEPACAM 产品)
- 别名
- GlialCAM Protein, MLC2A Protein, MLC2B Protein, 2900042E01Rik Protein, Hepn1 Protein, hepatic and glial cell adhesion molecule Protein, hepatocyte cell adhesion molecule Protein, HEPACAM Protein, Hepacam Protein
- 背景
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Background: Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.
Synonym: Hepatocyte Cell Adhesion Molecule, Protein HepaCAM, HEPACAM
- 分子量
- 24.1 kDa
- UniProt
- Q14CZ8
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