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HEPACAM Protein (His tag)

HEPACAM 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318573
发货至: 中国
  • 抗原 See all HEPACAM 蛋白
    HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 3
    • 1
    资源
    • 4
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This HEPACAM protein is labelled with His tag.
    原理
    Recombinant Human HEPACAM Protein (His Tag)
    序列
    Val34-Ser240
    产品特性
    Recombinant Human Hepatocyte Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Val34-Ser240 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HEPACAM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
    别名
    HEPACAM (HEPACAM 产品)
    别名
    GlialCAM Protein, MLC2A Protein, MLC2B Protein, 2900042E01Rik Protein, Hepn1 Protein, hepatic and glial cell adhesion molecule Protein, hepatocyte cell adhesion molecule Protein, HEPACAM Protein, Hepacam Protein
    背景

    Background: Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.

    Synonym: Hepatocyte Cell Adhesion Molecule, Protein HepaCAM, HEPACAM

    分子量
    24.1 kDa
    UniProt
    Q14CZ8
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