HEPACAM Protein (AA 34-240) (His tag)
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- 抗原 See all HEPACAM 蛋白
- HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
- 蛋白类型
- Recombinant
- 产品特性
- AA 34-240
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宿主
- 人
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资源
- 人细胞
- 标记
- This HEPACAM protein is labelled with His tag.
- 原理
- Recombinant Human Hepatocyte Cell Adhesion Molecule/HepaCAM (C-6His)
- 序列
- VNITSPVRLI HGTVGKSALL SVQYSSTSSD RPVVKWQLKR DKPVTVVQSI GTEVIGTLRP DYRDRIRLFE NGSLLLSDLQ LADEGTYEVE ISITDDTFTG EKTINLTVDV PISRPQVLVA STTVLELSEA FTLNCSHENG TKPSYTWLKD GKPLLNDSRM LLSPDQKVLT ITRVLMEDDD LYSCMVENPI SQGRSLPVKI TVYRRSSVDH HHHHH
- 产品特性
- Recombinant Human Hepatocyte Cell Adhesion Molecule/HEPACAM produced by transfected human cellss is a secreted protein with sequence (Val34-Ser240) of Human HEPACAM fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product HEPACAM 蛋白
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Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 34-240) protein (His tag)
Crystallography grade HEPACAM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 34-240) protein (His tag)Crystallography grade HEPACAM 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 262-416) protein (His tag)Crystallography grade HEPACAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 262-418) protein (His tag)Crystallography grade HEPACAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 34-416) protein (rho-1D4 tag)Crystallography grade HEPACAM 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 34-418) protein (rho-1D4 tag)Crystallography grade HEPACAM 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Hepatic and Glial Cell Adhesion Molecule (HEPACAM) protein (Myc-DYKDDDDK Tag)HEPACAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
- 别名
- hepacam (HEPACAM 产品)
- 别名
- GlialCAM Protein, MLC2A Protein, MLC2B Protein, 2900042E01Rik Protein, Hepn1 Protein, hepatic and glial cell adhesion molecule Protein, hepatocyte cell adhesion molecule Protein, HEPACAM Protein, Hepacam Protein
- Sub Type
- Fusionprotein
- 背景
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Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.
Alternative Names: Hepatocyte Cell Adhesion Molecule, Protein HepaCAM, HEPACAM - 分子量
- 24.09 kDa
- UniProt
- Q14CZ8
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