HRSP12 Protein (His tag)
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- 抗原 See all HRSP12 products
- HRSP12 (Heat-Responsive Protein 12 (HRSP12))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This HRSP12 protein is labelled with His tag.
- 原理
- Recombinant Human RIDA/HRSP12 Protein (His Tag)
- 序列
- Met 1-Leu137
- 产品特性
- Recombinant Human Heat-Responsive Protein 12 is produced by our E.coli expression system and the target gene encoding Met1-Leu137 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Heat-Responsive Protein 12 (HRSP12) (AA 1-137) protein (GST tag)
HRSP12 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Heat-Responsive Protein 12 (HRSP12) (AA 1-137) protein (His tag)HRSP12 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Heat-Responsive Protein 12 (HRSP12) (AA 2-137) protein (GST tag)HRSP12 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Heat-Responsive Protein 12 (HRSP12) protein (Myc-DYKDDDDK Tag)HRSP12 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 8.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- HRSP12 (Heat-Responsive Protein 12 (HRSP12))
- 别名
- RIDA/HRSP12 (HRSP12 产品)
- 别名
- P14.5 Protein, PSP Protein, UK114 Protein, HR12 Protein, HRP12 Protein, PSP1 Protein, Psp Protein, HRSP12 Protein, zgc:101025 Protein, zgc:92739 Protein, reactive intermediate imine deaminase A homolog Protein, ribonuclease UK114 Protein, heat-responsive protein 12 Protein, ribonuclease UK114 pseudogene Protein, RIDA Protein, Rida Protein, LOC698724 Protein, LOC711809 Protein, NGR_b07070 Protein, LOC100353046 Protein, hrsp12 Protein
- 背景
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Background: Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
Synonym: Ribonuclease UK114, 14.5 kDa Translational Inhibitor Protein, p14.5, Heat-Responsive Protein 12, UK114 Antigen Homolog, HRSP12, PSP
- 分子量
- 16.7 kDa
- UniProt
- P52758
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