Galectin 3 Protein (LGALS3) (His tag)
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- 抗原 See all Galectin 3 (LGALS3) 蛋白
- Galectin 3 (LGALS3)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This Galectin 3 protein is labelled with His tag.
- 原理
- Recombinant Human Galectin-3/LGALS3 Protein (His Tag)(Active)
- 序列
- Ala2-Ile250
- 产品特性
- Recombinant Human Galectin-3 is produced by our Mammalian expression system and the target gene encoding Ala2-Ile250 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to agglutinate human red blood cells.
- Top Product
- Discover our top product LGALS3 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 3 mM DTT.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Galectin 3 (LGALS3)
- 别名
- Galectin-3/LGALS3 (LGALS3 产品)
- 别名
- CBP 35 Protein, Gal-3 Protein, Galectin-3 Protein, leg3 Protein, galactoside-binding Protein, galectin-3 Protein, lectin Protein, soluble Protein, CBP35 Protein, GAL3 Protein, GALBP Protein, GALIG Protein, L31 Protein, LGALS2 Protein, MAC2 Protein, MGC52947 Protein, MGC75803 Protein, LGALS3 Protein, gal-3 Protein, GBP Protein, L-34 Protein, Mac-2 Protein, gal3 Protein, galectin 3 Protein, Galectin-3 Protein, avian beta-defensin 3 Protein, lectin, galactoside-binding, soluble, 3 L homeolog Protein, lectin, galactoside-binding, soluble, 3 Protein, galectin 2 Protein, lectin, galactose binding, soluble 3 Protein, LGALS3 Protein, leg3 Protein, AvBD3 Protein, lgals3.L Protein, lgals3 Protein, LGALS2 Protein, Lgals3 Protein
- 物质类
- Chemical
- 背景
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Background: Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma, and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth, as a result providing a new mechanism for tumor immune tolerance.
Synonym: Galectin-3, Gal-3, 35 kDa Lectin, Carbohydrate-Binding Protein 35, CBP35, Galactose-Specific Lectin 3, Galactoside-Binding Protein, GALBP, IgE-Binding Protein, L-31, Laminin-Binding Protein, Lectin L-29, Mac-2 Antigen, LGALS3, MAC2, P35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
- 分子量
- 27.2 kDa
- UniProt
- P17931
- 途径
- RTK signaling
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