GLB1 Protein (His tag)
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- 抗原 See all GLB1 蛋白
- GLB1 (Galactosidase, beta 1 (GLB1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This GLB1 protein is labelled with His tag.
- 原理
- Recombinant Human β-Galactosidase/GLB1 Protein (His Tag)
- 序列
- Leu24-Val677
- 产品特性
- Recombinant Human beta-Galactosidase is produced by our Mammalian expression system and the target gene encoding Leu24-Val677 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GLB1 蛋白
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Galactosidase, beta 1 (GLB1) protein (Fc Tag)
GLB1 宿主: E. coli 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE.
Galactosidase, beta 1 (GLB1) (AA 578-677) protein (GST tag)GLB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Galactosidase, beta 1 (GLB1) (AA 1-677) protein (GST tag)GLB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- GLB1 (Galactosidase, beta 1 (GLB1))
- 别名
- beta-Galactosidase/GLB1 (GLB1 产品)
- 别名
- EBP Protein, ELNR1 Protein, MPS4B Protein, DER Protein, XR Protein, 0610038K04Rik Protein, 1810027P18Rik Protein, glb Protein, CG9092 Protein, Dmel\\CG9092 Protein, beta-GAL Protein, beta-Gal-1 Protein, beta-gal Protein, gal Protein, lacZ-1 Protein, AW125515 Protein, Bge Protein, Bgl Protein, Bgl-e Protein, Bgl-s Protein, Bgl-t Protein, Bgs Protein, Bgt Protein, C130097A14Rik Protein, BGAL Protein, zgc:110823 Protein, ECK0341 Protein, JW0335 Protein, GLB Protein, galactosidase beta 1 Protein, dicarbonyl and L-xylulose reductase Protein, dicarbonyl L-xylulose reductase Protein, beta-D-galactosidase Protein, beta-galactosidase Protein, beta galactosidase Protein, galactosidase, beta 1 Protein, beta-galactosidase-like Protein, GLB1 Protein, DCXR Protein, Dcxr Protein, lacZ Protein, SSP_RS00525 Protein, lacH Protein, ECL_03691 Protein, Gal Protein, Glb1 Protein, glb1 Protein, VV2_1327 Protein, LOC100056371 Protein
- 背景
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Background: β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 100 mutations have been identified for β Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.
Synonym: Beta-Galactosidase, Acid Beta-Galactosidase, Lactase, Elastin Receptor 1, GLB1, ELNR1
- 分子量
- 74.6 kDa
- UniProt
- P16278
- 途径
- Glycosaminoglycan Metabolic Process
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