FZD5 Protein (His tag,Fc Tag)
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- 抗原 See all FZD5 蛋白
- FZD5 (Frizzled Family Receptor 5 (FZD5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FZD5 protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Human Frizzled-5/FZD5 Protein (His & Fc Tag)
- 序列
- Met 1-Pro 167
- 产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Pro 167) of human frizzled 5 (NP_003459.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product FZD5 蛋白
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Frizzled Family Receptor 5 (FZD5) (AA 1-585) protein (GST tag)
FZD5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 5 (FZD5) (AA 72-161) protein (GST tag)FZD5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 5 (FZD5) protein (Fc Tag)FZD5 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as determined by SDS-PAGE
Frizzled Family Receptor 5 (FZD5) (AA 27-238) protein (His tag)Crystallography grade FZD5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-238) protein (His tag)Crystallography grade FZD5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-585) protein (rho-1D4 tag)Crystallography grade FZD5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-585) protein (rho-1D4 tag)Crystallography grade FZD5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-167) protein (Fc Tag)FZD5 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FZD5 (Frizzled Family Receptor 5 (FZD5))
- 别名
- Frizzled-5/FZD5 (FZD5 产品)
- 别名
- C2orf31 Protein, HFZ5 Protein, 5330434N09Rik Protein, AI427138 Protein, Fz-5 Protein, Fz5 Protein, mFz5 Protein, Xfz5 Protein, frizzled5 Protein, frizzled5a Protein, fz5 Protein, fzd5-A Protein, fz2 Protein, fz8c Protein, fzd8c Protein, zg02 Protein, frizzled class receptor 5 Protein, frizzled class receptor 5 S homeolog Protein, FZD5 Protein, Fzd5 Protein, fzd5.S Protein, fzd5 Protein
- 背景
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Background: Wnt signaling is involved in a variety of embryonic development processes of nonvertebrates and vertebrates, where it determines cell motility, cell polarity, differentiation, proliferation and apoptosis, as well as formation of neural synapses. Various homologs of the Wingless protein, termed WNT factors, represent key mediators and act through a receptor complex comprised of members of the Frizzled and low density lipoprotein-related receptors (LRP). 19 WNTs, 10 Frizzled, and 2 LRP proteins have been identified. Frizzled is a family of G protein-coupled receptor proteins consisting of a divergent signal peptide, a highly conserved extracellular cysteine-rich domain (CRD), a variable-length linker region, a seven-pass transmembrane domain, and a variable-length C-terminal tail.Frizzled 5 (FZD5) is believed to be the receptor for the Wnt5A ligand, and also interactions with Wnt10B, Wnt2B, and Wnt 7A functionally. Recent studies of WNT5A/Frizzled-5 signaling have revealed an unexpected and novel role in orchestrating adaptive immunity in response to microbial stimulation. In addition, FZD5 is also implicated in the survival of mature neurons in the parafascicular nucleus of the thalamus.
Synonym: C2orf31,HFZ5
- 分子量
- 44 kDa
- NCBI登录号
- NP_003459
- 途径
- WNT signaling
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