FZD10 Protein (His tag)
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- 抗原 See all FZD10 蛋白
- FZD10 (Frizzled Family Receptor 10 (FZD10))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This FZD10 protein is labelled with His tag.
- 原理
- Recombinant Mouse Frizzled-10/FZD10 Protein (His Tag)
- 序列
- Met 1-Gly 162
- 产品特性
- A DNA sequence encoding the N-terminal segment of mouse FZD10 (NP_780493.1) (Met 1-Gly 162) was expressed, fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product FZD10 蛋白
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Frizzled Family Receptor 10 (FZD10) (AA 96-183) protein (GST tag)
FZD10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Frizzled Family Receptor 10 (FZD10) protein (Fc Tag)FZD10 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Frizzled Family Receptor 10 (FZD10) (AA 21-225) protein (His tag)Crystallography grade FZD10 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Frizzled Family Receptor 10 (FZD10) (AA 22-226) protein (His tag)Crystallography grade FZD10 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Frizzled Family Receptor 10 (FZD10) (AA 21-581) protein (rho-1D4 tag)Crystallography grade FZD10 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Frizzled Family Receptor 10 (FZD10) (AA 22-582) protein (rho-1D4 tag)Crystallography grade FZD10 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FZD10 (Frizzled Family Receptor 10 (FZD10))
- 别名
- Frizzled-10/FZD10 (FZD10 产品)
- 别名
- CD350 Protein, FZ-10 Protein, Fz10 Protein, FzE7 Protein, hFz10 Protein, cFz-10 Protein, Fz-10 Protein, Xfr9 Protein, Xfz10 Protein, frizzled-10 Protein, frizzled10 Protein, fz10 Protein, fze7 Protein, hfz10 Protein, fk48e04 Protein, fz4 Protein, fzb Protein, wu:fk48e04 Protein, zg04 Protein, Xfz10A Protein, fzd10a Protein, Xfz10B Protein, Xfz9 Protein, fzd10b Protein, fzd9 Protein, frizzled class receptor 10 Protein, frizzled class receptor 10 L homeolog Protein, frizzled class receptor 10 S homeolog Protein, FZD10 Protein, fzd10 Protein, Fzd10 Protein, fzd10.L Protein, fzd10.S Protein
- 背景
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Background: Frizzled-10, also known as Fz-10, CD350 and FZD10, is a multi-pass membrane protein which belongs to the G-protein coupled receptor Fz/Smo family. Frizzled-10 / FZD10 is abundantly expressed in the cerebellum, followed by cerebral cortex, medulla and spinal cord; very low levels in total brain, frontal lobe, temporal lobe and putamen. It is weakly expressed in adult brain, heart, lung, skeletal muscle, pancreas, spleen and prostate. Frizzled-10 / FZD10 is a receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Frizzled-10 / FZD10 may also be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Synonym: Fz-10
- 分子量
- 17.4 kDa
- NCBI登录号
- NP_780493
- 途径
- WNT signaling
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