FCGR1 Protein (His tag,AVI tag)
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- 抗原 See all FCGR1 蛋白
- FCGR1 (Fc Receptor, IgG, High Affinity I (FCGR1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This FCGR1 protein is labelled with His tag,AVI tag.
- 原理
- Recombinant Mouse CD64/FCGR1 Protein (His&AVI Tag)(Active)
- 序列
- Met 1-Pro 297
- 产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Pro 297) of mouse FCGR1 (NP_034316.1) was fused with a c-terminal polyhistidine tagged AVI tag at the C-terminus.
- 纯度
- > 97 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized mouse CD64-AVI at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1, The EC50 of biotinylated human IgG1 is 0.07-0.15 μg/ml.
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- Discover our top product FCGR1 蛋白
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Fc Receptor, IgG, High Affinity I (FCGR1) (AA 16-288) protein (His-Avi Tag)
FCGR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Receptor, IgG, High Affinity I (FCGR1) (AA 16-288) protein (His-Avi Tag,Biotin)FCGR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Receptor, IgG, High Affinity I (FCGR1) (AA 25-297) protein (His tag)FCGR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Receptor, IgG, High Affinity I (FCGR1) (Active) protein (His tag)FCGR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Fc Receptor, IgG, High Affinity I (FCGR1) (Active) protein (Biotin,His-Avi Tag)FCGR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Fc Receptor, IgG, High Affinity I (FCGR1) (AA 25-297) protein (His tag)Crystallography grade FCGR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Fc Receptor, IgG, High Affinity I (FCGR1) (AA 25-404) protein (rho-1D4 tag)Crystallography grade FCGR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Fc Receptor, IgG, High Affinity I (FCGR1) (AA 73-294) protein (His tag,T7 tag)FCGR1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, ELISA, WB, IP
Fc Receptor, IgG, High Affinity I (FCGR1) (AA 35-235) protein (His tag,T7 tag)FCGR1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, ELISA, WB, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FCGR1 (Fc Receptor, IgG, High Affinity I (FCGR1))
- 别名
- CD64/FCGR1 (FCGR1 产品)
- 别名
- CD64 Protein, CD64A Protein, FCRI Protein, IGFR1 Protein, AI323638 Protein, AV092959 Protein, FcgammaRI Protein, IGGHAFC Protein, FCGR1A Protein, Fcgr1 Protein, Fcgr1b Protein, Fc fragment of IgG receptor Ia Protein, Fc receptor, IgG, high affinity I Protein, FCGR1A Protein, Fcgr1 Protein, Fcgr1a Protein
- 背景
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Background: High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membrane glycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.
Synonym: High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; CD64;FcgammaRI;IGGHAFC
- 分子量
- 34.3 kDa
- NCBI登录号
- NP_034316
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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