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FCGR3B Protein (AA 1-200) (His tag)

FCGR3B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7195710
发货至: 中国
  • 抗原 See all FCGR3B 蛋白
    FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
    蛋白类型
    Recombinant
    产品特性
    AA 1-200
    宿主
    • 21
    • 2
    • 1
    • 1
    资源
    • 16
    • 4
    • 3
    • 1
    HEK-293 Cells
    标记
    This FCGR3B protein is labelled with His tag.
    原理
    Recombinant Human CD16b/FCGR3B Protein (aa 1-200, His Tag)
    序列
    Met 1-Ser 200
    产品特性
    A DNA sequence encoding the human CD16b (NP_000561.3) (Met 1-Ser 200) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product FCGR3B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
    别名
    CD16b/FCGR3B (FCGR3B 产品)
    别名
    CD16 Protein, CD16b Protein, FCG3 Protein, FCGR3 Protein, FCR-10 Protein, FCRIII Protein, FCRIIIb Protein, FcRIII Protein, Fc fragment of IgG receptor IIIb Protein, Fc receptor, IgG, low affinity III Protein, Fc fragment of IgG receptor IIIa Protein, Fc-gamma RIII Protein, FCGR3B Protein, Fcgr3 Protein, FCGR3A Protein, FCGR3 Protein
    背景

    Background: The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The research regarded that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development.

    Synonym: Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR6B,FCRIII,FCRIIIb

    分子量
    22.2 kDa
    NCBI登录号
    NP_000561
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