FCGR3B Protein (AA 17-200) (His-Avi Tag)
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- 抗原 See all FCGR3B 蛋白
- FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 17-200
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FCGR3B protein is labelled with His-Avi Tag.
- 原理
- Human Fc gamma RIIIB/CD16b (NA2) Protein
- 序列
- Gly17-Ser200 (NA2)
- 产品特性
- Recombinant Human Fc gamma RIIIB/CD16b (NA2) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly17-Ser200(NA2). The CD16b NA1 differ with the CD16b NA2 in AA36, 65, 82, and 106.The CD16b NA1 form carries R36, N65, D82, and V106, while the CD16b NA2 form carries S36,S65, N82, and I106.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.52 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-200) protein (His tag)
FCGR3B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) protein (His-Avi Tag,Biotin)FCGR3B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (Active) protein (Biotin)FCGR3B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-208) (Active) protein (His tag)FCGR3B 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-208) (Active) protein (His tag,AVI tag,Biotin)FCGR3B 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
- 别名
- Fc gamma RIIIB (FCGR3B 产品)
- 别名
- CD16 Protein, CD16b Protein, FCG3 Protein, FCGR3 Protein, FCR-10 Protein, FCRIII Protein, FCRIIIb Protein, FcRIII Protein, Fc fragment of IgG receptor IIIb Protein, Fc receptor, IgG, low affinity III Protein, Fc fragment of IgG receptor IIIa Protein, Fc-gamma RIII Protein, FCGR3B Protein, Fcgr3 Protein, FCGR3A Protein, FCGR3 Protein
- 背景
- Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
- 分子量
- 23.7 kDa. Due to glycosylation, the protein migrates to 47-53 kDa based on Tris-Bis PAGE result.
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